Blood pressure regulation: Every adaptation is an integration?

Michael J. Joyner, Jacqueline K. Limberg

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


This focused review serves to explore relevant issues in regard to blood pressure regulation and by doing so, provides the initial stimulus paper for the Thematic Review series "Blood Pressure Regulation" to be published in the European Journal of Applied Physiology over the coming months. In this introduction, we highlight how variable normal blood pressure can be and challenge the reader to take another look at some key concepts related to blood pressure regulation. We point out that there is frequently an underappreciated balance between peripheral vasodilation and systemic blood pressure regulation and ask the question: are changes in blood pressure, in effect, reasonable and integrated adaptations to the physiological challenge at hand? We conclude with the idea that blood pressure regulatory systems are both flexible and redundant; ensuring a wide variety of activities associated with life can be accompanied by a perfusion pressure that can serve multiple masters.

Original languageEnglish (US)
Pages (from-to)445-450
Number of pages6
JournalEuropean Journal of Applied Physiology
Issue number3
StatePublished - Mar 2014


  • Baroreflex
  • Cardiac output
  • Total peripheral resistance

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Physiology (medical)


Dive into the research topics of 'Blood pressure regulation: Every adaptation is an integration?'. Together they form a unique fingerprint.

Cite this