Birincil sistemik amiloidoz

Translated title of the contribution: Primary systemic amyloidosis

Archano Roy, Vivek Roy

Research output: Contribution to journalArticlepeer-review


Primary systemic amyloidosis is a rare disease with protean manifestations. Presence of nephrotic syndrome in the absence of diabetes and hypertension, cardiomyopathy in the absence of ischemia, restrictive cardiac defect, demyelinating polyneuropathy, or unexplained hepatomegaly should alert the physician to the possibility of amlyloidosis. Initial steps in the diagnostic evaluation of patients with suspected amyloidosis include serum and urine immunoelectrophoresis and immunofixation studies. Demonstration of amyloid material on tissue biopsy (eg, subcutaneous fat) is required for diagnosis. Availability of effective treatments has improved the outlook of patients with primary systemic amyloidosis. Early diagnosis is critical to optimizing the chances of effective therapy.

Translated title of the contributionPrimary systemic amyloidosis
Original languageTurkish
Pages (from-to)62-67
Number of pages6
Issue number1
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Medicine(all)


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