Biochemical Testing Relevant to Bone

Chee Kian Chew, Bart L. Clarke

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.

Original languageEnglish (US)
Pages (from-to)649-667
Number of pages19
JournalEndocrinology and Metabolism Clinics of North America
Issue number3
StatePublished - Sep 2017


  • Biochemical markers
  • Calcium
  • Metabolic bone disease
  • Parathyroid hormone
  • Parathyroid hormone-related protein
  • Phosphorus
  • Vitamin D

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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