Biochemical Testing Relevant to Bone

Chee Kian Chew; Bart L. Clarke

doi:10.1016/j.ecl.2017.04.003

Biochemical Testing Relevant to Bone

Chee Kian Chew, Bart L. Clarke

Endocrinology, Diabetes, Metabolism, and Nutrition

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.

Original language	English (US)
Pages (from-to)	649-667
Number of pages	19
Journal	Endocrinology and Metabolism Clinics of North America
Volume	46
Issue number	3
DOIs	https://doi.org/10.1016/j.ecl.2017.04.003
State	Published - Sep 2017

Keywords

Biochemical markers
Calcium
Metabolic bone disease
Parathyroid hormone
Parathyroid hormone-related protein
Phosphorus
Vitamin D

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.ecl.2017.04.003

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title = "Biochemical Testing Relevant to Bone",

abstract = "Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.",

keywords = "Biochemical markers, Calcium, Metabolic bone disease, Parathyroid hormone, Parathyroid hormone-related protein, Phosphorus, Vitamin D",

author = "Chew, {Chee Kian} and Clarke, {Bart L.}",

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AU - Chew, Chee Kian

AU - Clarke, Bart L.

PY - 2017/9

Y1 - 2017/9

N2 - Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.

AB - Laboratory biochemical testing is critical to the clinical understanding of bone disorders. Patients with skeletal diseases have underlying themes in their pathophysiology that would be impossible to detect without biochemical assessment of serum and urine minerals, vitamin D, parathyroid hormone, parathyroid hormone–related peptide, and bone turnover markers. Bone disorders are caused by abnormalities in signaling pathways that affect bone formation and resorption. Therapies for common bone diseases were developed in direct response to underlying biochemical abnormalities.

KW - Biochemical markers

KW - Calcium

KW - Metabolic bone disease

KW - Parathyroid hormone

KW - Parathyroid hormone-related protein

KW - Phosphorus

KW - Vitamin D

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DO - 10.1016/j.ecl.2017.04.003

M3 - Review article

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AN - SCOPUS:85020881070

SN - 0889-8529

VL - 46

SP - 649

EP - 667

JO - Endocrinology and Metabolism Clinics of North America

JF - Endocrinology and Metabolism Clinics of North America

IS - 3

ER -

Biochemical Testing Relevant to Bone

Abstract

Keywords

ASJC Scopus subject areas

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