Biobanks and personalized medicine

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


We provide a mini-review of how biobanks can support clinical genetics in the era of personalized medicine. We discuss types of biobanks, including disease specific and general biobanks not focused on one disease. We present considerations in setting up a biobank, including consenting and governance, biospecimens, risk factor and related data, informatics, and linkage to electronic health records for phenotyping. We also discuss the uses of biobanks and ongoing considerations, including genotype-driven recruitment, investigations of gene-environment associations, and the re-use of data generated from studies. Finally, we present a brief discussion of some of the unresolved issues, such as return of research results and sustaining biobanks over time. In summary, carefully designed biobanks can provide critical research and infrastructure support for clinical genetics in the era of personalized medicine.

Original languageEnglish (US)
Pages (from-to)50-55
Number of pages6
JournalClinical Genetics
Issue number1
StatePublished - Jul 2014


  • Biobanking
  • Biobanks
  • Biorepository
  • Personalized medicine

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


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