Barrett's Esophagus: Treatment Options

Jianmin Tian, Kenneth K. Wang

Research output: Chapter in Book/Report/Conference proceedingChapter


In the past few years, treatment for Barrett's esophagus has entered an important era with the development of a number of effective treatments to eradicate metaplastic mucosa, dysplasia, and early esophageal cancer. These endoscopic treatment options can be divided into two distinct categories: (1) tissue-acquiring methods such as endoscopic mucosal resection and endoscopic submucosal dissection, and (2) tissue ablation methods such as radiofrequency ablation, photodynamic therapy, argon plasma coagulation, cryoablation, multipolar electrocoagulation, and neodymium-doped yttrium aluminum garnet laser therapy. Currently endoscopic mucosal resection, radiofrequency ablation and photodynamic therapy are the mainstay of endoscopic therapies for Barrett's. Esophagectomy is predominantly indicated for patients with lesions that are more advanced than intramucosal cancer (more advanced than T1a), or those who have failed endoscopic management.

Original languageEnglish (US)
Title of host publicationPractical Manual of Gastroesophageal Reflux Disease
PublisherJohn Wiley and Sons
Number of pages24
ISBN (Print)9780470656266
StatePublished - Jan 25 2013


  • Argon plasma coagulation
  • Barrett's esophagus
  • Cryoablation
  • Endoscopic mucosal resection
  • Endoscopic submucosal dissection
  • Esophagectomy
  • Multipolar electrocoagulation
  • Photodynamic therapy
  • Radiofrequency ablation

ASJC Scopus subject areas

  • General Medicine


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