Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

Ee Hwa Kim; Younhee Kim; Mi Hyun Jang; Baek Vin Lim; Youn Jung Kim; Joo Ho Chung; Chang Ju Kim

doi:10.1016/S0304-3940(01)01948-6

Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

Ee Hwa Kim, Younhee Kim, Mi Hyun Jang, Baek Vin Lim, Youn Jung Kim, Joo Ho Chung, Chang Ju Kim

Neurosurgery

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. In food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus.

Original language	English (US)
Pages (from-to)	113-116
Number of pages	4
Journal	Neuroscience Letters
Volume	307
Issue number	2
DOIs	https://doi.org/10.1016/S0304-3940(01)01948-6
State	Published - Jul 13 2001

Keywords

Arcuate nucleus
Auricular acupuncture
Food intake
Hypothalamus
Immunohistochemistry
Neuropeptide Y
Paraventricular nucleus

ASJC Scopus subject areas

General Neuroscience

Access to Document

10.1016/S0304-3940(01)01948-6

Cite this

@article{6000ff14cc8645f5b625b4a88332fc24,

title = "Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats",

abstract = "The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. In food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus.",

keywords = "Arcuate nucleus, Auricular acupuncture, Food intake, Hypothalamus, Immunohistochemistry, Neuropeptide Y, Paraventricular nucleus",

author = "Kim, {Ee Hwa} and Younhee Kim and Jang, {Mi Hyun} and Lim, {Baek Vin} and Kim, {Youn Jung} and Chung, {Joo Ho} and Kim, {Chang Ju}",

note = "Funding Information: This work was supported by a Korea Research Foundation grant (KRF-99–003-F00393).",

year = "2001",

month = jul,

day = "13",

doi = "10.1016/S0304-3940(01)01948-6",

language = "English (US)",

volume = "307",

pages = "113--116",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

AU - Kim, Ee Hwa

AU - Kim, Younhee

AU - Jang, Mi Hyun

AU - Lim, Baek Vin

AU - Kim, Youn Jung

AU - Chung, Joo Ho

AU - Kim, Chang Ju

N1 - Funding Information: This work was supported by a Korea Research Foundation grant (KRF-99–003-F00393).

PY - 2001/7/13

Y1 - 2001/7/13

N2 - The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. In food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus.

AB - The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. In food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus.

KW - Arcuate nucleus

KW - Auricular acupuncture

KW - Food intake

KW - Hypothalamus

KW - Immunohistochemistry

KW - Neuropeptide Y

KW - Paraventricular nucleus

UR - http://www.scopus.com/inward/record.url?scp=0035854611&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035854611&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(01)01948-6

DO - 10.1016/S0304-3940(01)01948-6

M3 - Article

C2 - 11427313

AN - SCOPUS:0035854611

SN - 0304-3940

VL - 307

SP - 113

EP - 116

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 2

ER -

Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this