Atypical atrial flutter: Review of mechanisms, advances in mapping and ablation outcomes

Nway Le Ko Ko, Anil Sriramoju, Banveet Kaur Khetarpal, Komandoor Srivathsan

Research output: Contribution to journalArticlepeer-review


Purpose of reviewAtrial flutter (AFL) is the second most prevalent arrhythmia after atrial fibrillation (AF). It is a macro-reentrant tachycardia that is either cavotricuspid isthmus dependent (typical) or independent (atypical). This review aims at highlighting mechanism, diagnosis and treatment of atypical AFL and the recent developments in electroanatomic mapping.Recent findingsIncidence of left AFL is at an exponential rise presently with increase in AF ablation rates. The mechanism of left AFL is most often peri-mitral, roof-dependent or within pulmonary veins in preablated, in contrast to posterior or anterior wall low voltage areas in ablation naïve patients. Linear lesions, compared to pulmonary vein isolation alone, have higher incidence of atypical right or left AFL. Catheter ablation for atypical AFL is associated with lower rates of thromboembolic events, transfusions, and length of stay compared to typical AFL.SummaryAdvances in mapping have allowed rapid simultaneous acquisition of automatically annotated points in the atria and identification of details of macro-reentrant circuits, including zones of conduction block, scar, and slow conduction.

Original languageEnglish (US)
Pages (from-to)36-45
Number of pages10
JournalCurrent opinion in cardiology
Issue number1
StatePublished - Jan 1 2022


  • arrhythmia mapping
  • atrial flutter
  • atrial tachyarrhythmias
  • catheter ablation
  • reentry circuits

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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