Atrial fibrillation and stroke: Increasing stroke risk with intervention

Christopher V. DeSimone, Malini Madhavan, Elisa Ebrille, Alejandro A. Rabinstein, Paul A. Friedman, Samuel J. Asirvatham

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


This article focuses on the important newly recognized appreciation for the paradoxic increase in stroke and transient ischemic attack as a result of intervention meant to treat atrial fibrillation (AF) with the hope of decreasing stroke risk in the long term. The impact of silent cerebral lesions has recently been identified as a potentially major limitation, and the risks with AF ablation, as well as the present understanding of how risk can be minimized, are explained. This article provides a platform for newer study, changes in the way procedures are done, and possibly vascular-based stroke-reduction strategies.

Original languageEnglish (US)
Pages (from-to)87-94
Number of pages8
JournalCardiac Electrophysiology Clinics
Issue number1
StatePublished - Mar 2014


  • Ablation
  • Atrial fibrillation
  • Catheter
  • Embolism
  • Silent cerebral lesions

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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