Association Between Allergies and Psychiatric Disorders in Patients Undergoing Invasive Procedures

Dwight Aberle, Stephanie E. Wu, Rahmi Oklu, Joseph Erinjeri, Amy R. Deipolyi

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background Associations between allergies and psychiatric disorders have been reported in the context of depression and suicide; psychiatric disorders may affect pain perception. Objective To investigate the relationship of allergies with psychiatric disorders and pain perception in the context of invasive procedures, specifically during tunneled hemodialysis catheter placement. Methods We identified 89 patients (51 men, 38 women), mean age 66 years (range: 23–96), who underwent tunneled hemodialysis catheter placement (1/2014–2/2015), recording numeric rating scale pain scores, medications, psychiatric history, allergies, and smoking status. Results Of 89 patients, 47 patients had no allergies, and 42 had ≥1 allergy. Patients with allergies were more likely to have a pre-existing psychiatric disorder compared to those without allergies, odds ratio 2.6 (95% CI: 1.0–6.8). Having allergies did not affect procedural sedation or postprocedural pain scores. Multiple logistic regression with age, sex, smoking, presence of allergies, psychiatric history, inpatient/outpatient status, procedure time, and procedural sedation administration as inputs and postprocedural pain as the outcome showed that the only independent predictor was receiving procedural sedation (P = 0.005). Conclusions Findings corroborate anecdotal reports of allergies as a marker for psychiatric history. However, having allergies was not associated with increased pain or need for more sedation. Further studies could prospectively assess whether allergies and psychiatric disorders affect patient/doctor perceptions beyond pain during invasive procedures.

Original languageEnglish (US)
Pages (from-to)490-495
Number of pages6
Issue number5
StatePublished - Sep 2017


  • Allergy
  • Invasive procedure.
  • Pain
  • Psychiatric disorder
  • Sedation

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Arts and Humanities (miscellaneous)
  • Applied Psychology


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