ASPIRIN PROPHYLAXIS IN MIGRAINE

B. P. O'Neill, J. D. Mann

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

A prospective double-blind trial of aspirin prophylaxis demonstrated a reduction of more than 50% in headache frequency in 9 of 12 migraine patients. Response to aspirin did not correlate with age, duration of headache history, family history, or platelet ultrastructure. There is some evidence that response to aspirin is associated with raised platelet aggregation. This pilot study indicates that aspirin is effective in migraine prophylaxis.

Original languageEnglish (US)
Pages (from-to)1179-1181
Number of pages3
JournalThe Lancet
Volume312
Issue number8101
DOIs
StatePublished - Dec 2 1978

ASJC Scopus subject areas

  • General Medicine

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