Aortic valve replacement for Libman-Sacks endocarditis

Jack B. Keenan, Rajesh Janardhanan, Brandon T. Larsen, Zain Khalpey

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A 24-year-old man with systemic lupus erythematosus and antiphospholipid syndrome complicated by lupus nephritis presented with acute limb ischaemia secondary to an embolus. Following embolectomy, the patient underwent a transthoracic echocardiogram which revealed a large vegetation on all three cusps of the aortic valve. The patient was taken for an urgent aortic valve replacement with a mechanical valve. Cultures of one cusp remained sterile. Histopathological examination of the remaining two cusps revealed sterile fibrin-rich thrombotic vegetations characteristic of non-bacterial thrombotic endocarditis.

Original languageEnglish (US)
Article number215914
JournalBMJ case reports
StatePublished - 2016

ASJC Scopus subject areas

  • General Medicine


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