Antidepressant prescription pattern in a hospice program

Paulo R. Shiroma, Yonas E. Geda, Amit Mohan, Jarrett Richardson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Prevalence of treatable depression is as high as 25% among terminally ill patients. The incidence of antidepressant use was ascertained at the Mayo Hospice Program in Rochester, Minnesota, from June 1, 2007, to December 31, 2008. The 18-month cumulative probability to receive an antidepressant during hospice was estimated at 11.7%. Depression and selective serotonin reuptake inhibitors (SSRIs) were the most common clinical indication and class of antidepressant, respectively. Survival was the main predictor to receive an antidepressant with an odds ratio of 2.71 (95%CI: 1.60-4.60) for each additional day in hospice. Proper diagnostic tools for this population, education about the benefits of antidepressants in palliative care, and clear guidelines about antidepressant class and dosages are needed.

Original languageEnglish (US)
Pages (from-to)193-197
Number of pages5
JournalAmerican Journal of Hospice and Palliative Medicine
Issue number3
StatePublished - May 2011


  • antidepressive agents
  • hospice
  • incidence
  • palliative care
  • psychotropics
  • terminally ill

ASJC Scopus subject areas

  • General Medicine


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