TY - JOUR
T1 - Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors
T2 - ASCO and SNO endorsement of the congress of neurological surgeons guidelines
AU - Chang, Susan M.
AU - Messersmith, Hans
AU - Ahluwalia, Manmeet
AU - Andrews, David
AU - Brastianos, Priscilla K.
AU - Gaspar, Laurie E.
AU - Gatson, Na Tosha N.
AU - Jordan, Justin T.
AU - Khasraw, Mustafa
AU - Lassman, Andrew B.
AU - Maues, Julia
AU - Mrugala, Maciej
AU - Raizer, Jeffrey
AU - Schiff, David
AU - Stevens, Glen, Do, Phd
AU - Sumrall, Ashley
AU - Van Den Bent, Martin
AU - Vogelbaum, Michael A.
N1 - Publisher Copyright:
© 2019 American Society of Clinical Oncology. All rights reserved.
PY - 2019
Y1 - 2019
N2 - PURPOSE The Congress of Neurological Surgeons (CNS) has developed a series of guidelines for the treatment of adults with metastatic brain tumors, including systemic therapy and supportive care topics. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations. METHODS Two CNS guidelines were reviewed for developmental rigor by methodologists, and an independent multidisciplinary Expert Panel was formed to review the content and assess agreement with the recommendations. The Expert Panel voted to endorse the two guidelines, and ASCO and Society for Neuro-Oncology (SNO) independently reviewed and approved the ASCO/SNO guideline endorsement. RESULTS The ASCO/SNO Expert Panel determined that the recommendations from the CNS anticonvulsants and steroids guidelines, published January 9, 2019, are clear, thorough, and based on the most relevant scientific evidence. ASCO/SNO endorsed these two CNS guidelines with minor alterations. RECOMMENDATIONS Key recommendations include the following: prophylactic antiepileptic drugs were not recommended for routine use; and corticosteroids, specifically dexamethasone, were recommended for temporary symptomatic relief in patients with neurologic symptoms and signs related to mass effect from brain metastases. Additional information is available at www.asco.org/neurooncology-guidelines.
AB - PURPOSE The Congress of Neurological Surgeons (CNS) has developed a series of guidelines for the treatment of adults with metastatic brain tumors, including systemic therapy and supportive care topics. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations. METHODS Two CNS guidelines were reviewed for developmental rigor by methodologists, and an independent multidisciplinary Expert Panel was formed to review the content and assess agreement with the recommendations. The Expert Panel voted to endorse the two guidelines, and ASCO and Society for Neuro-Oncology (SNO) independently reviewed and approved the ASCO/SNO guideline endorsement. RESULTS The ASCO/SNO Expert Panel determined that the recommendations from the CNS anticonvulsants and steroids guidelines, published January 9, 2019, are clear, thorough, and based on the most relevant scientific evidence. ASCO/SNO endorsed these two CNS guidelines with minor alterations. RECOMMENDATIONS Key recommendations include the following: prophylactic antiepileptic drugs were not recommended for routine use; and corticosteroids, specifically dexamethasone, were recommended for temporary symptomatic relief in patients with neurologic symptoms and signs related to mass effect from brain metastases. Additional information is available at www.asco.org/neurooncology-guidelines.
UR - http://www.scopus.com/inward/record.url?scp=85063717455&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063717455&partnerID=8YFLogxK
U2 - 10.1200/JCO.18.02085
DO - 10.1200/JCO.18.02085
M3 - Review article
C2 - 30883246
AN - SCOPUS:85063717455
SN - 0732-183X
VL - 37
SP - 1130
EP - 1135
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
IS - 13
ER -