Anorectal melanoma

Suzanne Fastner; Tina J. Hieken; Robert R. McWilliams; John Hyngstrom

doi:10.1002/jso.27381

Anorectal melanoma

Suzanne Fastner, Tina J. Hieken, Robert R. McWilliams, John Hyngstrom

Research output: Contribution to journal › Review article › peer-review

Abstract

Anorectal melanoma is an aggressive mucosal melanoma subtype with a poor prognosis. Although recent advancements have been seen for cutaneous melanoma, the optimal treatment paradigm for management of anorectal melanoma is evolving. In this review, we highlight differences in the pathogenesis of mucosal versus cutaneous melanoma, new concepts of staging for mucosal melanoma, updates to surgical management of anorectal melanoma, and current data for adjuvant radiation and systemic therapy in this unique patient population.

Original language	English (US)
Pages (from-to)	635-644
Number of pages	10
Journal	Journal of Surgical Oncology
Volume	128
Issue number	4
DOIs	https://doi.org/10.1002/jso.27381
State	Published - Sep 15 2023

Keywords

adjuvant
anorectal melanoma
immunotherapy
local excision
melanoma
mucosal melanoma
proctectomy
radiotherapy

ASJC Scopus subject areas

Surgery
Oncology

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10.1002/jso.27381

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title = "Anorectal melanoma",

abstract = "Anorectal melanoma is an aggressive mucosal melanoma subtype with a poor prognosis. Although recent advancements have been seen for cutaneous melanoma, the optimal treatment paradigm for management of anorectal melanoma is evolving. In this review, we highlight differences in the pathogenesis of mucosal versus cutaneous melanoma, new concepts of staging for mucosal melanoma, updates to surgical management of anorectal melanoma, and current data for adjuvant radiation and systemic therapy in this unique patient population.",

keywords = "adjuvant, anorectal melanoma, immunotherapy, local excision, melanoma, mucosal melanoma, proctectomy, radiotherapy",

author = "Suzanne Fastner and Hieken, {Tina J.} and McWilliams, {Robert R.} and John Hyngstrom",

note = "Publisher Copyright: {\textcopyright} 2023 Wiley Periodicals LLC.",

year = "2023",

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doi = "10.1002/jso.27381",

language = "English (US)",

volume = "128",

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TY - JOUR

T1 - Anorectal melanoma

AU - Fastner, Suzanne

AU - Hieken, Tina J.

AU - McWilliams, Robert R.

AU - Hyngstrom, John

PY - 2023/9/15

Y1 - 2023/9/15

N2 - Anorectal melanoma is an aggressive mucosal melanoma subtype with a poor prognosis. Although recent advancements have been seen for cutaneous melanoma, the optimal treatment paradigm for management of anorectal melanoma is evolving. In this review, we highlight differences in the pathogenesis of mucosal versus cutaneous melanoma, new concepts of staging for mucosal melanoma, updates to surgical management of anorectal melanoma, and current data for adjuvant radiation and systemic therapy in this unique patient population.

AB - Anorectal melanoma is an aggressive mucosal melanoma subtype with a poor prognosis. Although recent advancements have been seen for cutaneous melanoma, the optimal treatment paradigm for management of anorectal melanoma is evolving. In this review, we highlight differences in the pathogenesis of mucosal versus cutaneous melanoma, new concepts of staging for mucosal melanoma, updates to surgical management of anorectal melanoma, and current data for adjuvant radiation and systemic therapy in this unique patient population.

KW - adjuvant

KW - anorectal melanoma

KW - immunotherapy

KW - local excision

KW - melanoma

KW - mucosal melanoma

KW - proctectomy

KW - radiotherapy

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UR - http://www.scopus.com/inward/citedby.url?scp=85164102104&partnerID=8YFLogxK

U2 - 10.1002/jso.27381

DO - 10.1002/jso.27381

M3 - Review article

C2 - 37395165

AN - SCOPUS:85164102104

SN - 0022-4790

VL - 128

SP - 635

EP - 644

JO - Journal of Surgical Oncology

JF - Journal of Surgical Oncology

IS - 4

ER -

Anorectal melanoma

Abstract

Keywords

ASJC Scopus subject areas

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