Animal models of fibrodysplasia ossificans progressiva

Frederick S. Kaplan; Eileen M. Shore; Robert J. Pignolo; David L. Glaser

doi:10.1385/BMM:3:3-4:229

Animal models of fibrodysplasia ossificans progressiva

Frederick S. Kaplan, Eileen M. Shore, Robert J. Pignolo, David L. Glaser

Hospital Internal Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Animal models of fibrodysplasia ossificans progressiva (FOP) are important for understanding the pathophysiology of FOP and for testing possible therapies. Laboratory-generated genetic animal models, each with features of FOP, provide the opportunity to better understand the biology of FOP, and to study the effectiveness and safety of currently available and emerging therapies.

Original language	English (US)
Pages (from-to)	229-234
Number of pages	6
Journal	Clinical Reviews in Bone and Mineral Metabolism
Volume	3
Issue number	3-4
DOIs	https://doi.org/10.1385/BMM:3:3-4:229
State	Published - Sep 1 2005

Keywords

Animal models
BMP4
Fibrodysplasia ossificans progressiva (FOP)
Heterotopic ossification

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Orthopedics and Sports Medicine
Endocrinology

Access to Document

10.1385/BMM:3:3-4:229

Cite this

@article{639659dbc9934dbca96472aa8ff12ae0,

title = "Animal models of fibrodysplasia ossificans progressiva",

abstract = "Animal models of fibrodysplasia ossificans progressiva (FOP) are important for understanding the pathophysiology of FOP and for testing possible therapies. Laboratory-generated genetic animal models, each with features of FOP, provide the opportunity to better understand the biology of FOP, and to study the effectiveness and safety of currently available and emerging therapies.",

keywords = "Animal models, BMP4, Fibrodysplasia ossificans progressiva (FOP), Heterotopic ossification",

author = "Kaplan, {Frederick S.} and Shore, {Eileen M.} and Pignolo, {Robert J.} and Glaser, {David L.}",

year = "2005",

month = sep,

day = "1",

doi = "10.1385/BMM:3:3-4:229",

language = "English (US)",

volume = "3",

pages = "229--234",

journal = "Clinical Reviews in Bone and Mineral Metabolism",

issn = "1534-8644",

publisher = "Humana Press",

number = "3-4",

}

TY - JOUR

T1 - Animal models of fibrodysplasia ossificans progressiva

AU - Kaplan, Frederick S.

AU - Shore, Eileen M.

AU - Pignolo, Robert J.

AU - Glaser, David L.

PY - 2005/9/1

Y1 - 2005/9/1

N2 - Animal models of fibrodysplasia ossificans progressiva (FOP) are important for understanding the pathophysiology of FOP and for testing possible therapies. Laboratory-generated genetic animal models, each with features of FOP, provide the opportunity to better understand the biology of FOP, and to study the effectiveness and safety of currently available and emerging therapies.

AB - Animal models of fibrodysplasia ossificans progressiva (FOP) are important for understanding the pathophysiology of FOP and for testing possible therapies. Laboratory-generated genetic animal models, each with features of FOP, provide the opportunity to better understand the biology of FOP, and to study the effectiveness and safety of currently available and emerging therapies.

KW - Animal models

KW - BMP4

KW - Fibrodysplasia ossificans progressiva (FOP)

KW - Heterotopic ossification

UR - http://www.scopus.com/inward/record.url?scp=25844513102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25844513102&partnerID=8YFLogxK

U2 - 10.1385/BMM:3:3-4:229

DO - 10.1385/BMM:3:3-4:229

M3 - Article

AN - SCOPUS:25844513102

SN - 1534-8644

VL - 3

SP - 229

EP - 234

JO - Clinical Reviews in Bone and Mineral Metabolism

JF - Clinical Reviews in Bone and Mineral Metabolism

IS - 3-4

ER -

Animal models of fibrodysplasia ossificans progressiva

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this