An electron-beam CT approach for transvenous coronary arteriography

P. J. Thomas, C. H. McCollough, E. L. Ritman

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Objective: The goal is to image the 3D anatomy of the major coronary arteries within a single breath-hold and using a single intravenous injection of contrast agent. Materials and Methods: With use of an electron-beam CT (EBCT) scanner, operated in its multislice scan mode (using all four target rings, each scanning two nominal 8 mm thick slices in a total time interval of 224 ms), a radiologically realistic thorax phantom containing a heart with coronary arteries (opacified with 40 mg iodine/ml) was scanned six times with the patient table advanced by a 2 mm step into the scanner between each scan. The normalized and scaled sinogram data were transferred to an off-line computer and reconstructed using our own implementation of a 3D algebraic reconstruction technique that takes into account the exact 3D relationship of the X-ray source and detector elements of the EBCT. Results: A single volume image consisting of 40 slices, at 2 mm intervals and each uniformly 3.7 mm thick, depicted the lumina of the coronary arteries with greater anatomic detail than the 'original' images at 8 mm, primarily because of the reduced partial volume effect. Conclusion: Our preliminary results suggest that EBCT, operated in multislice scan mode, may be useful for transvenous coronary angiography performed within a single breath-hold.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalJournal of computer assisted tomography
Issue number3
StatePublished - 1995


  • Angiography
  • Computed tomography, techniques
  • Computed tomography, three-dimensional

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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