Amyloid in the Lung

Misbah Baqir, Anja C. Roden, Teng Moua

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Amyloidosis is the term given to abnormal deposition of misfolded precursor proteins at single or multiple sites, leading to organ dysfunction or clinical signs and symptoms. Pulmonary manifestations are nonspecific and may be associated with several amyloid protein subtypes, commonly AL (light chain) and AA (autoimmune) amyloids. Signs or symptoms of amyloid disease may often involve more of the clinical abnormalities of other affected organs than the lungs themselves. Radiologic pulmonary findings include septal and parenchymal ground glass or nodular infiltrates, multiple nodules, cysts, and focal tracheobronchial abnormalities. Lymphadenopathy with or without calcification and pleural effusions has also been reported. Directed therapy is initiated in response to clinical signs or symptoms often as a result of systemic or secondary diseases or conditions. Long-term prognosis is more dependent on the extent of organ involvement where morbidity is often the highest in those with multisystemic disease.

Original languageEnglish (US)
Pages (from-to)299-310
Number of pages12
JournalSeminars in Respiratory and Critical Care Medicine
Issue number2
StatePublished - Apr 1 2020


  • AA amyloid
  • AL amyloid
  • amyloidosis
  • tracheobronchial amyloid
  • transthyretin amyloidosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'Amyloid in the Lung'. Together they form a unique fingerprint.

Cite this