Allergic contact dermatitis of the eyelids: An interdisciplinary review

Michal Turkiewicz, Ami Shah, Yul W. Yang, Aaron Mangold, Joanne Shen

Research output: Contribution to journalReview articlepeer-review


Purpose: A review of the published literature on the pathogenesis and treatment of eyelid allergic contact dermatitis and ocular surface involvement. Methods: Literature search of MEDLINE (Ovid) was conducted using for allergic contact dermatitis and disease of the eyelid or periorbital skin. Dates included in search criteria were from January 1, 2010 to January 12, 2023. 120 articles were reviewed by at least two authors. Results: Allergic eyelid contact dermatitis(ACD) is a Type IV hypersensitivity reaction to chemical exposure of sensitized eyelid skin. Most patients improve with avoidance strategies. Understanding chemicals that may trigger eyelid ACD, identifying allergens with patch testing, and use of topical steroids can help patients with this challenging disease. Conclusions: Recalcitrant allergic eyelid dermatitis can be addressed by an interdisciplinary team and avoidance strategies based on patch testing.

Original languageEnglish (US)
Pages (from-to)124-130
Number of pages7
JournalOcular Surface
StatePublished - Apr 2023


  • Allergens
  • Allergic contact dermatitis
  • Eyelid
  • Patch testing
  • Periorbital disease

ASJC Scopus subject areas

  • Ophthalmology


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