TY - JOUR
T1 - Age-related Prevalence of Valvular Regurgitation in Normal Subjects
T2 - A Comprehensive Color Flow Examination of 118, Volunteers
AU - Klein, Allan L.
AU - Burstow, Darryl J.
AU - Tajik, A. Jamil
AU - Zachariah, Prince K.
AU - Taliercio, Charles P.
AU - Taylor, Catherine L.
AU - Bailey, Kent R.
AU - Seward, James B.
N1 - Funding Information:
From the Division of Cardiovascular Diseases and Internal Med icine, the Division of Hypertension and Internal Medicine, and the Department of Health Sciences Research, Mayo Clinic and Mayo Foundation, Rochester. Supported in part by the Canadian Heart Foundation, Ottawa, Canada, and a grant from Mayo Foundation, Rochester, Min nesota. Reprint requests: A. Jamil Tajik, MD, Mayo Clinic, 200 First St. SW, Rochester, MN 55905. 27/l/14791
PY - 1990
Y1 - 1990
N2 - We prospectively assessed the influence of aging on the prevalence of valvular regurgitation by using color flow imaging. One hundred eighteen healthy volunteers (21 to 82 years old) had a two-dimensional Doppler echocardiographic study that included color flow imaging to assess valvular regurgitation and that was semiquantitated by mapping the dimensions of the color flow regurgitant jet in orthogonal views. The subjects were divided into two groups: group 1 consisted of subjects who were younger than 50 years old (n = 61), and group 2,consisted of subjects who were at least 50 years old (n = 57). Mitral regurgitation was detected in 57 (48%) of the 118 subjects: 24 subjects (39%) in group 1 and 33 subjects (58%) in group 2. The severity of mitral regurgitation was trivial to mild. Aortic regurgitation was detected in 13 (11%) of the 118 subjects, all in group 2. The severity was trivial to mild. Tricuspid regurgitation was detected in 77 (65%) of the 118 subjects: 35 (57%) in group 1 and 42 (74%) in group 2. The severity was trivial to mild. Pulmonary regurgitation was detected in 24 (31%) of 78 subjects: nine (22%) in group 1 and 15 (41%) in group 2. The severity was trivial. These findings suggest that valvular regurgitation of a trivial or mild degree is a frequent finding in normal subjects and that it increases with age.
AB - We prospectively assessed the influence of aging on the prevalence of valvular regurgitation by using color flow imaging. One hundred eighteen healthy volunteers (21 to 82 years old) had a two-dimensional Doppler echocardiographic study that included color flow imaging to assess valvular regurgitation and that was semiquantitated by mapping the dimensions of the color flow regurgitant jet in orthogonal views. The subjects were divided into two groups: group 1 consisted of subjects who were younger than 50 years old (n = 61), and group 2,consisted of subjects who were at least 50 years old (n = 57). Mitral regurgitation was detected in 57 (48%) of the 118 subjects: 24 subjects (39%) in group 1 and 33 subjects (58%) in group 2. The severity of mitral regurgitation was trivial to mild. Aortic regurgitation was detected in 13 (11%) of the 118 subjects, all in group 2. The severity was trivial to mild. Tricuspid regurgitation was detected in 77 (65%) of the 118 subjects: 35 (57%) in group 1 and 42 (74%) in group 2. The severity was trivial to mild. Pulmonary regurgitation was detected in 24 (31%) of 78 subjects: nine (22%) in group 1 and 15 (41%) in group 2. The severity was trivial. These findings suggest that valvular regurgitation of a trivial or mild degree is a frequent finding in normal subjects and that it increases with age.
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U2 - 10.1016/S0894-7317(14)80299-X
DO - 10.1016/S0894-7317(14)80299-X
M3 - Article
C2 - 2310593
AN - SCOPUS:0025138156
SN - 0894-7317
VL - 3
SP - 54
EP - 63
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 1
ER -