@article{e70edb0458f34bda8623f267d0dec6b6,
title = "Advancing Research on the Complex Interrelations between Atrial Fibrillation and Heart Failure: A Report from a US National Heart, Lung, and Blood Institute Virtual Workshop",
abstract = "The interrelationships between atrial fibrillation (AF) and heart failure (HF) are complex and poorly understood, yet the number of patients with AF and HF continues to increase worldwide. Thus, there is a need for initiatives that prioritize research on the intersection between AF and HF. This article summarizes the proceedings of a virtual workshop convened by the US National Heart, Lung, and Blood Institute to identify important research opportunities in AF and HF. Key knowledge gaps were reviewed and research priorities were proposed for characterizing the pathophysiological overlap and deleterious interactions between AF and HF; preventing HF in people with AF; preventing AF in individuals with HF; and addressing symptom burden and health status outcomes in AF and HF. These research priorities will hopefully help inform, encourage, and stimulate innovative, cost-efficient, and transformative studies to enhance the outcomes of patients with AF and HF.",
keywords = "atrial fibrillation, heart failure, research",
author = "Al-Khatib, {Sana M.} and Benjamin, {Emelia J.} and Albert, {Christine M.} and Alvaro Alonso and Cynthia Chauhan and Chen, {Peng Sheng} and Curtis, {Anne B.} and Patrice Desvigne-Nickens and Ho, {Jennifer E.} and Lam, {Carolyn S.P.} and Link, {Mark S.} and Patton, {Kristen K.} and Redfield, {Margaret M.} and Michiel Rienstra and Yves Rosenberg and Renate Schnabel and Spertus, {John A.} and Stevenson, {Lynne Warner} and Hills, {Mellanie True} and Voors, {Adriaan A.} and Cooper, {Lawton S.} and Go, {Alan S.}",
note = "Funding Information: Dr Al-Khatib receives consulting fees from Milestone Pharmaceuticals, speaking and consulting fees from Medtronic, and speaking fees from Bristol-Myers Squibb/ Pfizer. Dr. Albert receives research funding from St Jude Medical, Abbott, and Roche Diagnostics. Dr Albert receives consultant fees from Roche Diagnostics. Dr Chen has received from Medtronic research equipment for his laboratory. Dr Curtis receives fees from Medtronic for speaking and serving on a data monitoring board; fees from Abbott for speaking and serving on an advisory board; fees from Novartis for serving on an advisory board; fees from Sanofi Aventis and Janssen Pharmaceuticals for serving on an advisory board; and speaking fees from Milestone Pharmaceuticals. Dr Lam is supported by a Clinician Scientist Award from the National Medical Research Council of Singapore; has received research support from Boston Scientific, Bayer, Roche Diagnostics, AstraZeneca, Medtronic, and Vifor Pharma; and has served as a consultant or on the advisory board/steering committee/executive committee for Boston Scientific, Bayer, Roche Diagnostics, AstraZeneca, Medtronic, Vifor Pharma, Novartis, Amgen, Merck, Janssen Research Funding Information: & Development LLC, Menarini, Boehringer Ingelheim, Novo Nordisk, Abbott Diagnostics, Corvia, Stealth BioTherapeutics, JanaCare, Biofourmis, Darma, Applied Therapeutics, MyoKardia, WebMD Global LLC, Radcliffe Group Ltd, and Corpus. Dr Schnabel reports receiving speaking fees from Bristol-Myers Squibb/Pfizer. Dr Sper-tus receives consulting fees from Bayer, AstraZeneca, Janssen, Amgen, and Merck; has equity in Outcomes Instruments; and serves on the Scientific Advisory Board for United Healthcare and Board of Directors for BlueCross BlueShield of Kansas City. Dr Spertus holds copyright of the Kansas City Cardiomyopathy Questionnaire, the Seattle Angina Questionnaire, and the Peripheral Artery Questionnaire. Dr Stevenson is an unpaid consultant to Abbott Diagnostics and Biotronik and an unpaid chair of Data Safety and Monitoring Board for Livanova. Dr Voors receives consultant fees and research grants from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Cytokinetics, Novartis, and Roche Diagnostics. Dr Go has received a research grant through his institution (Kaiser Permanente Northern California) from iRhythm Technologies. The other authors report no conflicts. Funding Information: Dr Benjamin receives research funding from the US National Institutes of Health, National Heart, Lung, and Blood Institute through grants R01HL092577 and 1R01HL128914 and from the American Heart Association through grant 18SFRN34110082. Dr Albert receives research funding from the US National Institutes of Health (grant R01HL116690). Publisher Copyright: {\textcopyright} 2020 Lippincott Williams and Wilkins. All rights reserved.",
year = "2020",
month = jun,
day = "9",
doi = "10.1161/CIRCULATIONAHA.119.045204",
language = "English (US)",
volume = "141",
pages = "1915--1926",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "23",
}