Advancements in the Application of Ultrasound Elastography in the Cervix

Juntao Shao, Guilian Shi, Zhengqin Qi, Jingjing Zheng, Shigao Chen

Research output: Contribution to journalReview articlepeer-review


Ultrasound elastography is a modern imaging technique that has developed rapidly in recent years. It enables objective measurement of tissue stiffness, a physical property intuitive to the human sense of touch. This novel technology has become a hotspot and plays a major role in scientific research and academic practice. Presently, ultrasound elastography has been used in the identification of benign and malignant tumors in superficial organs, such as breast and thyroid, providing clinically accurate diagnosis and treatment. The method has also been widely used for the liver, kidney, prostate, lymph nodes, blood vessels, skin and muscle system. In the application of cervical lesions, ultrasound elastography can distinguish normal cervix from abnormal cervix and differentiate benign from malignant lesions. It can significantly improve the diagnostic specificity for cervical cancer and is also useful for assessing infiltration depth and stage of cervical cancer, as well as predicting chemoradiotherapy treatment response. For cervical evaluation during pregnancy, ultrasound elastography is useful for assessing cervical softening and predicting premature delivery and outcome of induced labor. This article reviews the principles of ultrasound elastography as well as the current status and limitations in its application for cervical lesions and the cervix during pregnancy.

Original languageEnglish (US)
Pages (from-to)2048-2063
Number of pages16
JournalUltrasound in Medicine and Biology
Issue number8
StatePublished - Aug 2021


  • Cervical cancer
  • Cervical lesions
  • Cervix during pregnancy
  • Normal cervix
  • Ultrasound elastography

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics


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