Adrenomedullin: An autocrine/paracrine factor for cardiorenal protection

Toshihiro Tsuruda, John C. Burnett

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.

Original languageEnglish (US)
Pages (from-to)625-627
Number of pages3
JournalCirculation research
Issue number6
StatePublished - Apr 5 2002


  • Adrenomedullin
  • Autocrine
  • Knockout
  • Paracrine
  • Transgenic

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine


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