Abstract
In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.
Original language | English (US) |
---|---|
Pages (from-to) | 625-627 |
Number of pages | 3 |
Journal | Circulation research |
Volume | 90 |
Issue number | 6 |
DOIs | |
State | Published - Apr 5 2002 |
Keywords
- Adrenomedullin
- Autocrine
- Knockout
- Paracrine
- Transgenic
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine