Adrenocortical carcinoma metastatic to the orbit

George B. Bartley, R. Jean Campbell, Diva R. Salomão, Elizabeth A. Bradley, W. Richard Marsh, Uldis Bite

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Purpose: To describe the clinical course and histopathologic features of a patient with adrenocortical carcinoma metastatic to the orbit. Methods: Case report and literature review. Results: A 24-year-old man first came to medical attention because of symptoms referable to a 4.47-kg, nonfunctioning carcinoma of the left adrenal cortex. Several metastases ensued, including a large tumor to the right superior lateral bony orbit with extension to the brain, temporalis fossa, and orbit proper. The tumor was resected with the use of a combined neurosurgical, ophthalmic, and craniofacial approach. The patient died of widespread metastatic disease 15 months after the orbital operation. Conclusions: Metastasis to the orbit from adrenocortical carcinoma is rare. Surgical resection is the treatment of choice, with adjunctive radiation therapy and chemotherapy in some cases. The prognosis is poor.

Original languageEnglish (US)
Pages (from-to)215-220
Number of pages6
JournalOphthalmic Plastic and Reconstructive Surgery
Issue number3
StatePublished - May 2001

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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