@article{0339ebbac3c149f9a006f9ffcc5e6741,
title = "Adjusted Survival Curves Improve Understanding of Multivariable Cox Model Results",
abstract = "Kaplan-Meier survival curves are the most common methods for unadjusted group comparison of outcomes in orthopedic research. However, they may be misleading due to an imbalance of confounders between patient groups. The Cox model is frequently used to adjust for confounders, but graphical display of adjusted survival curves is not commonly utilized. We describe the circumstances when adjusted survival curves are useful in orthopedic research, describe and use 2 different methods to obtain adjusted curves, and illustrate how they can improve understanding of the multivariable Cox model results. We further provide practical strategies for identifying the need for and performing adjusted survival curves. Please visit the following https://youtu.be/ys0hy2CiMCA for a video that explains the highlights of the paper in practical terms.",
keywords = "Cox model, confounding, survival analysis, survival curves, total joint arthroplasty",
author = "Lundgreen, {Carly S.} and Larson, {Dirk R.} and Atkinson, {Elizabeth J.} and Devick, {Katrina L.} and Lewallen, {David G.} and Berry, {Daniel J.} and {Maradit Kremers}, Hilal and Crowson, {Cynthia S.}",
note = "Funding Information: Funding: This work was funded by a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant P30AR76312 ) and the American Joint Replacement Research-Collaborative . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Funding Information: Funding: This work was funded by a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant P30AR76312) and the American Joint Replacement Research-Collaborative. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",
year = "2021",
month = oct,
doi = "10.1016/j.arth.2021.06.002",
language = "English (US)",
volume = "36",
pages = "3367--3371",
journal = "Journal of Arthroplasty",
issn = "0883-5403",
publisher = "Churchill Livingstone",
number = "10",
}