ACUPUNCTURE ANÆSTHESIA

Robert W. Brennan; Johannes Veldhuis; Richard Chu

doi:10.1016/S0140-6736(73)90895-7

ACUPUNCTURE ANÆSTHESIA

Robert W. Brennan, Johannes Veldhuis, Richard Chu

Endocrinology, Diabetes, Metabolism, and Nutrition

Research output: Contribution to journal › Letter › peer-review

4 Scopus citations

Original language	English (US)
Pages (from-to)	849-850
Number of pages	2
Journal	The Lancet
Volume	302
Issue number	7833
DOIs	https://doi.org/10.1016/S0140-6736(73)90895-7
State	Published - Oct 13 1973

ASJC Scopus subject areas

General Medicine

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@article{42c4d90e33114fd3ba9923e3e75267da,

title = "ACUPUNCTURE AN{\AE}STHESIA",

author = "Brennan, {Robert W.} and Johannes Veldhuis and Richard Chu",

note = "Funding Information: of patients at the National Cancer Institute (undoubtedly including many of the patients reported by Hirshaut et at.). Only 12 Burkitt{\textquoteright}s lymphoma patients were reported by us then, in contrast to the 29 reported in our subsequent papers, but it is reassuring to find that Hirshaut et al.{\textquoteright}s series confirms our finding that a number of American Burkitt{\textquoteright}s lymphoma patients are negative. As of July 1, 1973, we have studied sera from 73 patients with Burkitt{\textquoteright}s lymphoma and have found that the sera from 12 of these do not contain detectable antibodies to E.B. virus. The point that we have made in our previous publications that should be emphasised again, however, is that we are impressed by the number of American Burkitt{\textquoteright}s lymphoma patients with high E.B.-virus titres not because we necessarily believe that E.B. virus causes Burkitt{\textquoteright}s lymphoma but because this represents another parameter, in addition to the clinical features and time-space clus- tering 9,10 in which American and African Burkitt{\textquoteright}s lymphomas are similar. Determination of the xtiology of Burkitt{\textquoteright}s lymphoma is less likely to come through serology than through the detection of the viral genome in the patients{\textquoteright} tumours and not in controls. Some of these studies do continue to implicate E.B. virus as a possible cause of Burkitt{\textquoteright}s lymphoma,{"}-13 although Klein{\textquoteright}A has found two typical Burkitt tumour specimens from African patients that do not contain the E.B.-virus-associated nuclear antigen found in almost all other fresh tumours. We would agree with Hirshaut and his colleagues that it is still premature to assume that E.B. virus causes Burkitt{\textquoteright}s tumour in any country, but we also think that it is premature to state that Burkitt{\textquoteright}s tumour has a different astiotogy in Africa than it has in the United States. Public Health Service, National Institutes of Health, Bethesda, Maryland 20014, U.S.A.",

year = "1973",

month = oct,

day = "13",

doi = "10.1016/S0140-6736(73)90895-7",

language = "English (US)",

volume = "302",

pages = "849--850",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

number = "7833",

}

TY - JOUR

T1 - ACUPUNCTURE ANÆSTHESIA

AU - Brennan, Robert W.

AU - Veldhuis, Johannes

AU - Chu, Richard

N1 - Funding Information: of patients at the National Cancer Institute (undoubtedly including many of the patients reported by Hirshaut et at.). Only 12 Burkitt’s lymphoma patients were reported by us then, in contrast to the 29 reported in our subsequent papers, but it is reassuring to find that Hirshaut et al.’s series confirms our finding that a number of American Burkitt’s lymphoma patients are negative. As of July 1, 1973, we have studied sera from 73 patients with Burkitt’s lymphoma and have found that the sera from 12 of these do not contain detectable antibodies to E.B. virus. The point that we have made in our previous publications that should be emphasised again, however, is that we are impressed by the number of American Burkitt’s lymphoma patients with high E.B.-virus titres not because we necessarily believe that E.B. virus causes Burkitt’s lymphoma but because this represents another parameter, in addition to the clinical features and time-space clus- tering 9,10 in which American and African Burkitt’s lymphomas are similar. Determination of the xtiology of Burkitt’s lymphoma is less likely to come through serology than through the detection of the viral genome in the patients’ tumours and not in controls. Some of these studies do continue to implicate E.B. virus as a possible cause of Burkitt’s lymphoma,"-13 although Klein’A has found two typical Burkitt tumour specimens from African patients that do not contain the E.B.-virus-associated nuclear antigen found in almost all other fresh tumours. We would agree with Hirshaut and his colleagues that it is still premature to assume that E.B. virus causes Burkitt’s tumour in any country, but we also think that it is premature to state that Burkitt’s tumour has a different astiotogy in Africa than it has in the United States. Public Health Service, National Institutes of Health, Bethesda, Maryland 20014, U.S.A.

PY - 1973/10/13

Y1 - 1973/10/13

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VL - 302

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JO - The Lancet

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IS - 7833

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ACUPUNCTURE ANÆSTHESIA

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