ACR appropriateness criterias definitive external-beam irradiation in stage T1 and T2 prostate cancer

Paul L. Nguyen, Ayal Aizer, Dean G. Assimos, Anthony V. D'Amico, Steven J. Frank, Alexander R. Gottschalk, Gary S. Gustafson, I. Chow Joe Hsu, Patrick W. Mclaughlin, Gregory Merrick, Seth A. Rosenthal, Timothy N. Showalter, Al V. Taira, Neha Vapiwala, Yoshiya Yamada, Brian J. Davis

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Purpose: To present the most updated American College of Radiology consensus guidelines formed from an expert panel on the appropriate use of external-beam radiation to manage stage T1 and T2 prostate cancer. Methods: The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. Results: The panel summarized the most recent and relevant literature on the topic and voted on 3 clinical variants illustrating the appropriate dose, techniques, and use of adjuvant hormone therapy with externalbeam radiation for low-risk, intermediate-risk, and high-risk prostate cancer. Numerical rating and commentary reflecting the panel consensus was given for each treatment approach in each variant. Conclusions: External-beam radiation is a key component of the curative management of T1 and T2 prostate cancer. By combining the most recent medical literature and expert opinion, this guideline can aid clinicians in the appropriate use of external-beam radiation for prostate cancer.

Original languageEnglish (US)
Pages (from-to)278-288
Number of pages11
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Issue number3
StatePublished - 2014


  • Appropriateness criteria
  • External-beam radiation
  • Prostate cancer
  • Radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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