ACR appropriateness criteria ® Local-regional Recurrence (LR) and salvage surgery breast cancer

Michele Y. Halyard, Nabil Wasif, Eleanor E.R. Harris, Douglas W. Arthur, Lisa Bailey, Jennifer R. Bellon, Lisa Carey, Sharad Goyal, Kathleen C. Horst, Meena S. Moran, Shannon M. MacDonald, Bruce G. Haffty

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Despite the success of both breast conserving surgery and mastectomy, some women will experience a local-regional recurrence (LRR) of their breast cancer. Predictors for LRR after breast-conserving therapy or mastectomy have been identified, including patient, tumor, and treatment-related factors. The role of surgery, radiation, and chemotherapy as treatment has evolved over time and many patients now have the potential for salvage after LRR. This review of LRR of breast cancer and management recommendations, including the use of common clinical scenarios, represents a compilation of evidence-based data and expert opinion of the American College of Radiology Appropriateness Criteria Expert Panel on local-regional recurrence. The American College of Radiology Appropriateness Criteria are evidencebased guidelines for specific clinical conditions that are reviewed every 2 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.

Original languageEnglish (US)
Pages (from-to)178-182
Number of pages5
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Issue number2
StatePublished - Apr 2012


  • Appropriateness criteria
  • Breast cancer
  • Local-regional recurrence
  • Relapse
  • Salvage therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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