Acoustoelasticity modeling of bladder tissue nonlinearity: Ex vivo study

Mahdi Bayat, Aprana Singh, Jeremy Webb, Viksit Kumar, Adriana Gregory, Azra Alizad, Mostafa Fatemi

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A method for measurement of the bladder wall nonlinear elasticity is presented. The method is based on acoustoelasticity modeling of the bladder tissue modulus of elasticity changes at different volumetric loading levels. At each loading volume, tissue strain is obtained from the real-time images. Using acoustic radiation force, a transient Lamb wave is excited on the bladder wall and shear elasticity is obtained from 2-D Fourier analysis of tissue motion spatial-temporal dispersion maps. Experimental elasticity and strain data are then used to obtain nonlinear elasticity parameter, A, using non-linear least square optimization. The method was tested in 9 ex vivo porcine bladder samples before and after treatment with formalin. The estimated nonlinearity parameter, A, was significantly higher in the treated samples compared to intact (P < 0.0021).

Original languageEnglish (US)
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
StatePublished - Oct 31 2017
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: Sep 6 2017Sep 9 2017

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727


Other2017 IEEE International Ultrasonics Symposium, IUS 2017
Country/TerritoryUnited States


  • Acoustoelasticity
  • Bladder
  • Lamb wave
  • Shear modulus
  • Strain

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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