Accuracy of an electronic monitoring and reminder device for use with travoprost eye drops

Catherine Boden, Arthur Sit, Robert N. Weinreb

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Purpose: To evaluate the accuracy of a prototype electronic device for recording eye drop usage. Participants and Methods: Ten volunteers were randomly assigned to one of five usage patterns designed to mimic common patterns of use in glaucoma patients from 100% compliant to 50% compliant. All participants agreed to adhere to a pre-determined "dosing" schedule for 15 days using the monitoring/reminder device to instill artificial tears. Participants also recorded drop usage in a diary. The main outcome measures were device accuracy and reproducibility. Device accuracy was defined as the magnitude of the difference between the diary and device output for three variables: date, number of drops, and instillation time. Results: Date stamping by the device was 100% accurate. The mean ± SD time difference between the device and the diary was -2.0 ± 19.7 minutes when data from all participants was pooled. In seven of the ten participants, the device did not record at least one drop. The mean ± SD difference in the number of drops recorded by the device minus the diary was 0.16 ± 0.97 when data from all participants was pooled. Conclusions: The prototype compliance reminder/monitoring device may underestimate compliance in some patients. The date and time stamping mechanisms were generally accurate and reproducible.

Original languageEnglish (US)
Pages (from-to)30-34
Number of pages5
JournalJournal of glaucoma
Issue number1
StatePublished - Feb 2006

ASJC Scopus subject areas

  • Ophthalmology


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