A review on microbial alkaline proteases

P. Ellaiah, B. Srinivasulu, K. Adinarayana

Research output: Contribution to journalArticlepeer-review


Alkaline proteases are of considerable interest in view of their activity and stability at alkaline pH. This review describes the preteases that can resist extreme alkaline environments produced by a wide range of alkalophilic microorganisms. Different isolation methods which enable the screening and selection of promising organisms for industrial production are discussed. The various nutritional and environmental parameters affecting the production of alkaline proteases are delineated. The production of proteases by free and immobilized whole cells is discussed. The purification, properties, and applications of these proteases are also discussed.

Original languageEnglish (US)
Pages (from-to)690-704
Number of pages15
JournalJournal of Scientific and Industrial Research
Issue number9
StatePublished - Sep 2002

ASJC Scopus subject areas

  • General


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