A review of the growing evidence base for pediatric psychopharmacology

Elizabeth A. Pappadopulos, B. Tate Guelzow, Carrie Wong, Melissa Ortega, Peter S. Jensen

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


This article provides an update of pediatric psychopharmacologic treatment evidence and focuses on six classes of medications in pediatric populations: psychostimulants, mood stabilizers, SSRIs, tricyclic antidepressants, antipsychotic agents, and other agents. The evidence is organized by disorder so that it is most useful to practicing clinicians. We begin each section with a brief introduction and summary of the findings published before January 1998. Priority is given to clinical trials that use random assignment and use of a comparison group (ie, placebo-control, head-to-head comparison, or cross-over design). Serious concerns remain about the efficacy and safety of many of these agents for use in children and adolescents. While a great progress is being made, there is clearly much work left to be done.

Original languageEnglish (US)
Pages (from-to)817-855
Number of pages39
JournalChild and Adolescent Psychiatric Clinics of North America
Issue number4
StatePublished - Oct 2004

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health


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