A practical approach to the diagnosis of spinal cord lesions

Romina Mariano, Eoin P. Flanagan, Brain G. Weinshenker, Jacqueline Palace

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

Original languageEnglish (US)
Pages (from-to)187-200
Number of pages14
JournalPractical neurology
Issue number3
StatePublished - Jun 1 2018


  • MRI
  • clinical neurology
  • myelopathy

ASJC Scopus subject areas

  • Clinical Neurology


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