TY - JOUR
T1 - A Population-Based Study of Anterior Ischemic Optic Neuropathy Following Cataract Surgery
AU - Mansukhani, Sasha A.
AU - Chen, John J.
AU - Fairbanks, Aaron M.
AU - Foster, Robert C.
AU - Erie, Jay C.
AU - Baratz, Keith H.
AU - Hodge, David O.
AU - Bhatti, M. Tariq
N1 - Funding Information:
Sasha A Mansukhani is a pediatric ophthalmologist and neuro-ophthalmologist at the Mayo Clinic Health Systems and Assistant Professor of Ophthalmology in the Mayo Clinic College of Medicine, Minnesota. She has completed a fellowship in pediatric ophthalmology and strabismus from Emory University and the Mayo Clinic, and a neuro-ophthalmology fellowship from the Mayo Clinic. Her research interests include epidemiology studies, retinopathy of prematurity, and pediatric optic nerve disorders.
Funding Information:
Funding/Support: This study was supported by the Mayo Foundation . Financial Disclosures: The authors indicate no financial support or conflicts of interest. All authors attest that they meet the current ICMJE criteria for authorship.
Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2021/2
Y1 - 2021/2
N2 - Purpose: To determine if there is an increased incidence rate of post–cataract surgery (pcs) anterior ischemic optic neuropathy (AION) compared to spontaneous AION (sAION). Design: Retrospective, population-based cohort. Methods: Patients diagnosed with AION from January 1, 1990, through December 31, 2016, while residing in Olmsted County, Minnesota. Patients with cataract surgery preceding AION were included in the pcsAION cohort defined in 2 ways: AION within 2 months and AION within 1 year of cataract surgery. The incidence rates of pcsAION and sAION were compared using Poisson regression models. Results: During the study period, 102 residents developed AION. The median age was 65 years (range, 40-90 years), 44 (43.1%) were female. Twenty of 102 (19.6%) patients had previous cataract surgery, of which 2 and 9 developed AION within 2 months and 1 year of surgery, respectively. The annual incidence rate of pcsAION within 2 months of surgery (8.6 per 100,000) was not significantly greater than the annual incidence rate of sAION (6.9 per 100,000; P = .78). However, the annual incidence rate of pcsAION within 1 year of surgery (38.9 per 100,000) was significantly higher than the incidence rate of sAION (6.5 per 100,000; P < .001). Conclusion: The incidence of AION is increased in the first year after cataract surgery, but not in the early (i.e., 2 months) postoperative period.
AB - Purpose: To determine if there is an increased incidence rate of post–cataract surgery (pcs) anterior ischemic optic neuropathy (AION) compared to spontaneous AION (sAION). Design: Retrospective, population-based cohort. Methods: Patients diagnosed with AION from January 1, 1990, through December 31, 2016, while residing in Olmsted County, Minnesota. Patients with cataract surgery preceding AION were included in the pcsAION cohort defined in 2 ways: AION within 2 months and AION within 1 year of cataract surgery. The incidence rates of pcsAION and sAION were compared using Poisson regression models. Results: During the study period, 102 residents developed AION. The median age was 65 years (range, 40-90 years), 44 (43.1%) were female. Twenty of 102 (19.6%) patients had previous cataract surgery, of which 2 and 9 developed AION within 2 months and 1 year of surgery, respectively. The annual incidence rate of pcsAION within 2 months of surgery (8.6 per 100,000) was not significantly greater than the annual incidence rate of sAION (6.9 per 100,000; P = .78). However, the annual incidence rate of pcsAION within 1 year of surgery (38.9 per 100,000) was significantly higher than the incidence rate of sAION (6.5 per 100,000; P < .001). Conclusion: The incidence of AION is increased in the first year after cataract surgery, but not in the early (i.e., 2 months) postoperative period.
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U2 - 10.1016/j.ajo.2020.08.020
DO - 10.1016/j.ajo.2020.08.020
M3 - Article
C2 - 32818451
AN - SCOPUS:85096400003
SN - 0002-9394
VL - 222
SP - 157
EP - 165
JO - American journal of ophthalmology
JF - American journal of ophthalmology
ER -