Abstract
Background/Aim: Locoregional recurrences of head and neck cancers are often associated with a poor overall survival (OS). Outcomes may be improved with individualized treatments considering a patient’s lifespan. A specific scoring system for estimating OS prognoses is presented. Patients and Methods: In a preceding study of these 60 patients, Eastern Cooperative Oncology Group performance score (ECOG 0-1 versus 2, p=0.002) and N-stage (N0-1 versus N2, p=0.004) were identified as independent predictors of OS. Results: In the current study, the following scoring points were assigned: ECOG performance score 2=0 points, ECOG performance score 0-1=1 point, N2=0 points, N0-1=1 point. Patient scores were 0, 1 or 2 points with 3-year OS rates of 0%, 46% and 83%, respectively (p<0.0001). On multivariable analysis, differences remained significant (p<0.0001). Conclusion: This new scoring system includes three groups of patients with significantly different OS prognoses and can assist physicians when designing individualized therapy for locoregional recurrences of head and neck cancer.
Original language | English (US) |
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Pages (from-to) | 1611-1613 |
Number of pages | 3 |
Journal | Anticancer research |
Volume | 38 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2018 |
Keywords
- Head
- Locoregional recurrence
- Neck cancer
- Overall survival
- Radiotherapy
- Scoring system
ASJC Scopus subject areas
- Oncology
- Cancer Research