A new pattern of lipomatosis of nerve: Case report

Nikhil K. Prasad, Mark A. Mahan, Benjamin M. Howe, Kimberly K. Amrami, Robert J. Spinner

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Lipomatosis of nerve (LN) is a rare disorder of peripheral nerves that produces proliferation of interfascicular adipose tissue. It may be associated with soft-tissue and bony overgrowth within the affected nerve territory. LN has been almost exclusively reported in appendicular peripheral nerves; the median nerve at the wrist and palm is among the most common locations. The authors present a new pattern of LN that shows circumferential proliferation of fat around the epineurium of the nerve. They believe that this case and the two other documented examples in the literature (also affecting cervical and thoracic spinal nerves) share the same new pattern of LN. Defining the full spectrum of adipose lesions of the nerve and establishing a cause-effect relationship with nerve-territory overgrowth disorders may offer options for future management through targeted nerve lesioning.

Original languageEnglish (US)
Pages (from-to)933-937
Number of pages5
JournalJournal of neurosurgery
Issue number3
StatePublished - Mar 2017


  • Lipomatosis of nerve
  • Osseous hypertrophy
  • Peripheral nerve
  • Segmental overgrowth

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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