A new paradigm in viral resistance

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The rapid mutation of RNA viruses allows for the acquisition of resistance to drugs directly targeting viral proteins. Therefore, a novel approach to the development of antivirals centers on targeting host factors critical to viral replication. A recent report has brought to light the potential for RNA viruses to also develop resistance against compounds targeting crucial host factors, suggesting that a combination of drugs with various targets may be necessary for preventing resistance.

Original languageEnglish (US)
Pages (from-to)1515-1517
Number of pages3
JournalCell Research
Issue number11
StatePublished - Nov 2012

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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