Abstract
Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse.
Original language | English (US) |
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Pages (from-to) | 141-147 |
Number of pages | 7 |
Journal | Journal of the American Academy of Dermatology |
Volume | 78 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2018 |
Keywords
- cutaneous squamous cell carcinoma
- immunosuppression
- management
- radiotherapy
- risk stratification
- sentinel lymph node biopsy
- staging
ASJC Scopus subject areas
- Dermatology