TY - JOUR
T1 - A multicenter evaluation of commercial attenuation compensation techniques in cardiac SPECT using phantom models
AU - O’connor, Michael K.
AU - Kemp, Brad
AU - Anstett, Frank
AU - Christian, Paul
AU - Ficaro, Edward P.
AU - Frey, Eric
AU - Jacobs, Mark
AU - Kritzman, James N.
AU - Pooley, Robert A.
AU - Wilk, Michael
N1 - Funding Information:
Funding for this study was through an internal grant from Mayo Foundation for Education and Research.
Funding Information:
Paul Christian— development work on the Beacon system was partially funded through a research grant from Picker Corp.
PY - 2002
Y1 - 2002
N2 - Background. Our goal was to evaluate the ability of current commercially available attenuation compensation (AC) techniques to correct for the effects of attenuation, scatter, and loss of resolution with depth, in a series of standardized phantom experiments. Methods and Results. The following systems were evaluated: Hawkeye (GE Medical Systems), Profile (Siemens Medical Systems), Vantage Pro (ADAC Laboratories), TAC (SMV America), M-STEP (University of Michigan, Ann Arbor), TransAct (Elscint), Beacon (Marconi Systems), and PET Advance (GE Medical Systems). Studies were performed with the use of normal and ischemic myocardium in air and with technetium 99m or fluorine 18 in torso phantoms. There was considerable variation in the uniformity of short-axis slices and defect contrast for images acquired in air (no AC). AC improved the uniformity of activity throughout normal myocardium. A simulated hot liver resulted in severe artifacts and was only partially corrected by many systems. A high-quality attenuation map appears to be an important determinant of image quality. No system produced AC images of comparable quality to those obtained in the absence of scatter/attenuating media. Conclusions. There are significant differences in the ability of commercial AC systems to reduce artifacts due to attenuation and scatter. These differences are partly the result of non-AC factors (collimation, orbit, etc). In general, systems that generated high-quality attenuation maps yielded the best results.
AB - Background. Our goal was to evaluate the ability of current commercially available attenuation compensation (AC) techniques to correct for the effects of attenuation, scatter, and loss of resolution with depth, in a series of standardized phantom experiments. Methods and Results. The following systems were evaluated: Hawkeye (GE Medical Systems), Profile (Siemens Medical Systems), Vantage Pro (ADAC Laboratories), TAC (SMV America), M-STEP (University of Michigan, Ann Arbor), TransAct (Elscint), Beacon (Marconi Systems), and PET Advance (GE Medical Systems). Studies were performed with the use of normal and ischemic myocardium in air and with technetium 99m or fluorine 18 in torso phantoms. There was considerable variation in the uniformity of short-axis slices and defect contrast for images acquired in air (no AC). AC improved the uniformity of activity throughout normal myocardium. A simulated hot liver resulted in severe artifacts and was only partially corrected by many systems. A high-quality attenuation map appears to be an important determinant of image quality. No system produced AC images of comparable quality to those obtained in the absence of scatter/attenuating media. Conclusions. There are significant differences in the ability of commercial AC systems to reduce artifacts due to attenuation and scatter. These differences are partly the result of non-AC factors (collimation, orbit, etc). In general, systems that generated high-quality attenuation maps yielded the best results.
KW - Attenuation correction
KW - Multicenter trial
KW - Single photon emission computed tomography
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U2 - 10.1067/mnc.2002.122676
DO - 10.1067/mnc.2002.122676
M3 - Article
C2 - 12161711
AN - SCOPUS:0036657431
SN - 1071-3581
VL - 9
SP - 361
EP - 376
JO - Journal of Nuclear Cardiology
JF - Journal of Nuclear Cardiology
IS - 4
ER -