@inproceedings{8448db99751847fc9fae7e4fd1e3aa30,
title = "A MICROFLUIDIC DEVICE FOR CULTURING INTACT LIVER TISSUE",
abstract = "Hepatocytes are highly differentiated cells that lose phenotype and function after 3 to 5 days in vitro. It is well appreciated in the field that hepatic function may be rescued by introducing support cast cells (e.g. stromal cells) or components of extracellular matrix (ECM). In this study, we developed a microfluidic device for cultivating intact liver tissue that retains native cellular and matrix elements and demonstrated maintenance of high level of hepatic function for at least 7 days.",
keywords = "Ex vivo cultures, Hepatocytes, Microfluidics, Needle core biopsy",
author = "{de Hoyos-Vega}, {Jose M.} and Hong, {Hye Jin} and Gulnaz Stybayeva and Alexander Revzin",
note = "Funding Information: This study was supported in part by the grants Regenerative Medicine Minnesota (RMM 101617 TR 004) and NIH (DK107255). Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",
year = "2021",
language = "English (US)",
series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "443--444",
booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}