A dense search challenge phantom fabricated with pixel-based 3D printing for precise detectability assessment

Scott S. Hsieh, Kai Mei, Nadav Shapira, Picha Shunhavanich, J. Webster Stayman, Cynthia H. McCollough, Grace Gang, Shuai Leng, Michael Geagen, Lifeng Yu, Peter B. Noël

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The performance of a CT scanner for detectability tasks is difficult to precisely measure. Metrics such as contrast-to-noise ratio, modulation transfer function, and noise power spectrum do not predict detectability in the context of nonlinear reconstruction. We propose to measure detectability using a dense search challenge: a phantom is embedded with hundreds of target objects at random locations, and a human or numerical observer analyzes the reconstruction and reports on suspected locations of all target objects. The reported locations are compared to ground truth to produce a figure of merit, such as area under the curve (AUC), that is sensitive to the acquisition dose and the dose efficiency of the CT scanner. We used simulations to design such a dense search challenge phantom and found that detectability could be measured with precision better than 5%. Test 3D prints using the PixelPrint technique showed the feasibility of this technique.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2023
Subtitle of host publicationPhysics of Medical Imaging
EditorsLifeng Yu, Rebecca Fahrig, John M. Sabol
PublisherSPIE
ISBN (Electronic)9781510660311
DOIs
StatePublished - 2023
EventMedical Imaging 2023: Physics of Medical Imaging - San Diego, United States
Duration: Feb 19 2023Feb 23 2023

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12463
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2023: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego
Period2/19/232/23/23

Keywords

  • 3D printed phantoms
  • CT assessment
  • detectability
  • model observer

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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