TY - JOUR
T1 - A core review of temperature regimens and neuroprotection during cardiopulmonary bypass
T2 - Does rewarming rate matter?
AU - Grigore, Alina M.
AU - Murray, Catherine Friederich
AU - Ramakrishna, Harish
AU - Djaiani, George
PY - 2009/12
Y1 - 2009/12
N2 - Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effects has been the use of hypothermia. Although numerous studies have addressed the issue, the question of whether the use of hypothermia during CPB attenuates the impact of central nervous system consequences remains unresolved. However, data clearly demonstrate that hyperthermia is to be avoided in the perioperative period, necessitating careful rewarming strategies if hypothermia is used during CPB. Selecting and understanding the impact of the temperature-monitoring site is important to accurately estimate cerebral temperature and to avoid inadvertent surges in brain temperature. In this article, we review the literature regarding the impact of hypothermia and rewarming rates during cardiac surgery.
AB - Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effects has been the use of hypothermia. Although numerous studies have addressed the issue, the question of whether the use of hypothermia during CPB attenuates the impact of central nervous system consequences remains unresolved. However, data clearly demonstrate that hyperthermia is to be avoided in the perioperative period, necessitating careful rewarming strategies if hypothermia is used during CPB. Selecting and understanding the impact of the temperature-monitoring site is important to accurately estimate cerebral temperature and to avoid inadvertent surges in brain temperature. In this article, we review the literature regarding the impact of hypothermia and rewarming rates during cardiac surgery.
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U2 - 10.1213/ANE.0b013e3181c04fea
DO - 10.1213/ANE.0b013e3181c04fea
M3 - Review article
C2 - 19923500
AN - SCOPUS:73949158444
SN - 0003-2999
VL - 109
SP - 1741
EP - 1751
JO - Anesthesia and analgesia
JF - Anesthesia and analgesia
IS - 6
ER -