A Comprehensive Approach to Pouch Disorders

Kevin P. Quinn, Amy Lightner, William Alvis Faubion, Laura E. H. Raffals

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice for patients with medically refractory ulcerative colitis (UC) or indeterminate colitis, UC with colonic dysplasia or neoplasia, and familial adenomatous polyposis. In general, patients experience good function outcomes and quality of life with an IPAA. Although pouchitis is the most well-recognized and frequent complication after IPAA, a number of additional inflammatory, postsurgical, structural, neoplastic, and functional complications may occur, resulting in pouch dysfunction. We herein provide a comprehensive review of pouch function and an approach to diagnosis and management of pouch complications.

Original languageEnglish (US)
Pages (from-to)460-471
Number of pages12
JournalInflammatory bowel diseases
Issue number3
StatePublished - Feb 21 2019


  • ileal pouch-anal anastomosis
  • pouch dysfunction
  • pouchitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology


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