A centrosome kinase modulates antitumor drug sensitivity

Jeffrey L. Salisbury

doi:10.1016/j.ccr.2010.07.008

A centrosome kinase modulates antitumor drug sensitivity

Jeffrey L. Salisbury

Biochemistry and Molecular Biology

Research output: Contribution to journal › Short survey › peer-review

Abstract

In this issue of Cancer Cell, Ahmed and coworkers identify SIK2 as a centrosome kinase and show that it controls the localization of the centriole linker protein C-Nap1. Interference with SIK2 function results in loss of normal mitotic spindle function and increased sensitivity to antitumor drugs.

Original language	English (US)
Pages (from-to)	99-100
Number of pages	2
Journal	Cancer cell
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/j.ccr.2010.07.008
State	Published - Aug 2010

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1016/j.ccr.2010.07.008

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title = "A centrosome kinase modulates antitumor drug sensitivity",

abstract = "In this issue of Cancer Cell, Ahmed and coworkers identify SIK2 as a centrosome kinase and show that it controls the localization of the centriole linker protein C-Nap1. Interference with SIK2 function results in loss of normal mitotic spindle function and increased sensitivity to antitumor drugs.",

author = "Salisbury, {Jeffrey L.}",

year = "2010",

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AU - Salisbury, Jeffrey L.

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AB - In this issue of Cancer Cell, Ahmed and coworkers identify SIK2 as a centrosome kinase and show that it controls the localization of the centriole linker protein C-Nap1. Interference with SIK2 function results in loss of normal mitotic spindle function and increased sensitivity to antitumor drugs.

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DO - 10.1016/j.ccr.2010.07.008

M3 - Short survey

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AN - SCOPUS:77955534003

SN - 1535-6108

VL - 18

SP - 99

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JO - Cancer cell

JF - Cancer cell

IS - 2

ER -

A centrosome kinase modulates antitumor drug sensitivity

Abstract

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