Abstract
A biosensor based on an array of vertically aligned carbon nanofibers (CNFs) grown by plasma enhanced chemical vapor deposition is found to be effective for the simultaneous detection of dopamine (DA) and serotonin (5-HT) in the presence of excess ascorbic acid (AA). The CNF electrode outperforms the conventional glassy carbon electrode (GCE) for both selectivity and sensitivity. Using differential pulse voltammetry (DPV), three distinct peaks are seen for the CNF electrode at 0.13. V, 0.45. V, and 0.70. V for the ternary mixture of AA, DA, and 5-HT. In contrast, the analytes are indistinguishable in a mixture using a GCE. For the CNF electrode, the detection limits are 50. nM for DA and 250. nM for 5-HT.
Original language | English (US) |
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Pages (from-to) | 434-438 |
Number of pages | 5 |
Journal | Biosensors and Bioelectronics |
Volume | 42 |
Issue number | 1 |
DOIs | |
State | Published - Apr 5 2013 |
Keywords
- Biosensor
- Carbon nanofiber
- Dopamine
- Nanoelectrode array
- Serotonin
ASJC Scopus subject areas
- Biotechnology
- Biophysics
- Biomedical Engineering
- Electrochemistry