1,25-Dihydroxyvitamin D-mediated hypercalcemia in a renal transplant recipient

Muralikrishna S. Golconda, Tlmothy S. Larson, Llsa G. Külb, Rajiv Kumar

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Hypercalcemia occurs in 10 to 30% of renal transplant recipients and is most often due to persistent hyperparathyroidism. Herein we describe a patient with a history of hyperparathyroidism who sought medical assessment because of recurrence of hypercalcemia 7 years after a successful renal transplantation. The hypercalcemia was associated with a normal serum phosphate level, a low to normal parathyroid hormone level, virtually undetectable levels of parathyroid hormone-related protein, and increased 1,25-dihydroxyvitamin D levels. Further assessment led to the diagnosis of an underlying lymphoma. To our knowledge, this is the first report of 1,25- dihydroxyvitamin D-mediated hypercalcemia in a renal transplant recipient with lymphoma. The possibility of an underlying lymphoproliferative disorder should be considered in the differential diagnosis of hypercalcemia in a renal transplant recipient.

Original languageEnglish (US)
Pages (from-to)32-36
Number of pages5
JournalMayo Clinic proceedings
Issue number1
StatePublished - 1996

ASJC Scopus subject areas

  • Medicine(all)


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