Functional Reorganization of the Brain: response to Alzheimer’s Pathology

Increasingly sophisticated imaging techniques have enabled scientists to study subtle processes and abnormalities in the brain. One technique, functional magnetic resonance imaging (fMRI), can now detect tiny alterations in the chemical activity that connects brain cells of different regions. These alterations may represent disease-related changes to synapses and other neurological structures involved in brain cell communication. During Alzheimer's disease, synaptic changes occur at very early stages of the disease, and they can reveal important information about how Alzheimer's progresses over time