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Dive into the research topics where Georges Mer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Targeted Inhibition of DNA Repair Protein TIRR with Aptamers to Counteract Resistance of Ovarian Cancer Cells to PARP Inhibitors
Mer, G. (PI)
6/1/20 → …
Project: Research project
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Structural biology of DNA damage response in chromatin
Mer, G. (PI)
National Institute of General Medical Sciences
5/1/20 → 2/28/25
Project: Research project
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Structural basis of RNF168-mediated ubiquitin signaling at chromosomal DNA breaks
Mer, G. (PI)
9/22/15 → 8/31/20
Project: Research project
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Post-translational Modifications in DNA Damage Response: a Structural Perspective
Mer, G. (CoPI)
4/1/08 → 12/31/24
Project: Research project
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Adolescent-onset multisystem proteinopathy due to a novel VCP variant
Soontrapa, P., Seven, N. A., Liewluck, T., Cui, G., Mer, G. & Milone, M., Jan 2024, In: Neuromuscular Disorders. 34, p. 89-94 6 p.Research output: Contribution to journal › Article › peer-review
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Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes
Palani, S., Machida, Y., Alvey, J. R., Mishra, V., Welter, A. L., Cui, G., Bragantini, B., Botuyan, M. V., Cong, A. T. Q., Mer, G., Schellenberg, M. J. & Machida, Y. J., Dec 2024, In: Nature communications. 15, 1, 2064.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1
Hu, Q., Botuyan, M. V. & Mer, G., Mar 2024, In: Journal of Biological Chemistry. 300, 3, 105775.Research output: Contribution to journal › Article › peer-review
Open Access -
Mechanisms of RNF168 nucleosome recognition and ubiquitylation
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J. R., Botuyan, M. V. & Mer, G., Mar 7 2024, In: Molecular Cell. 84, 5, p. 839-853.e12Research output: Contribution to journal › Article › peer-review
Open Access -
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Kilgas, S., Syed, A., Toolan-Kerr, P., Swift, M. L., Roychoudhury, S., Sarkar, A., Wilkins, S., Quigley, M., Poetsch, A. R., Botuyan, M. V., Cui, G., Mer, G., Ule, J., Drané, P. & Chowdhury, D., Dec 2024, In: Nature communications. 15, 1, 8438.Research output: Contribution to journal › Article › peer-review
Open Access