Projects per year
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Collaborations and top research areas from the last five years
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Engineering tissue inhibitor of metalloproteinases-2 (TIMP-2) for triple negative breast cancer therapy
Radisky, E. E. S. & Radisky, E. S.
3/1/21 → 2/29/24
Project: Research project
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Engineering selective inhibition of metalloproteinases by tissue inhibitors of metalloproteinases (R01 GM132100 RESUB - *TIMPs)
Radisky, E. E. S. & Radisky, E. S.
National Institute of General Medical Sciences
4/1/20 → 12/31/23
Project: Research project
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Exploiting new approaches for selective inhibition of trypsins
National Institute of General Medical Sciences
1/1/22 → 11/30/23
Project: Research project
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Proteolysis in the Pathogenesis of ARDS
Downey, G. P., Radisky, D. C. & Radisky, E. S.
National Heart, Lung, and Blood Institute
12/22/21 → 11/30/23
Project: Research project
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Targeting the IL-6 - SPINK1 regulatory axis in ovarian clear cell carcinoma
4/1/18 → 7/31/20
Project: Research project
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Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix Metalloproteinase Inhibitor
Bonadio, A., Wenig, B. L., Hockla, A., Radisky, E. S. & Shifman, J. M., Jul 1 2023, In: Journal of Molecular Biology. 435, 13, 168095.Research output: Contribution to journal › Article › peer-review
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The roles of proteases in prostate cancer
Koistinen, H., Kovanen, R. M., Hollenberg, M. D., Dufour, A., Radisky, E. S., Stenman, U. H., Batra, J., Clements, J., Hooper, J. D., Diamandis, E., Schilling, O., Rannikko, A. & Mirtti, T., Jun 2023, In: IUBMB Life. 75, 6, p. 493-513 21 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
Hayun, H., Coban, M., Bhagat, A. K., Ozer, E., Alfonta, L., Caulfield, T. R., Radisky, E. S. & Papo, N., Dec 2023, In: Scientific reports. 13, 1, 5186.Research output: Contribution to journal › Article › peer-review
Open Access -
Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma
Duch, P., Díaz-Valdivia, N., Ikemori, R., Gabasa, M., Radisky, E. S., Arshakyan, M., Gea-Sorlí, S., Mateu-Bosch, A., Bragado, P., Carrasco, J. L., Mori, H., Ramírez, J., Teixidó, C., Reguart, N., Fillat, C., Radisky, D. C. & Alcaraz, J., Aug 2022, In: Matrix Biology. 111, p. 207-225 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma
Mehner, C., Hockla, A., Coban, M., Madden, B., Estrada, R., Radisky, D. C. & Radisky, E. S., Aug 2022, In: Journal of Biological Chemistry. 298, 8, 102146.Research output: Contribution to journal › Article › peer-review
Open Access