Cardiovascular Medicine

Projects

Projects per year 1984 2002 2003 2004 2006 2009 2011 2013 2015 2016 2017 2021 2022 2023 2025

• 15 Active
• 77 Finished

Projects per year

Search results

• Finished

  Novel Therapeutics for Cardiovascular Disease

  Sangaralingham, S. J., Burnett, J. C. J. & Malany, S.

  National Heart, Lung, and Blood Institute

  5/12/22 → 4/30/24

  Project: Research project

  • atrial natriuretic factor receptor A 100%
  • Cardiovascular Diseases 32%
  • Atrial Natriuretic Factor 25%
  • Aldosterone 11%
  • Vasodilation 10%

• Mechanisms of Clinical and Hemodynamic Response to Pulmonary Vasodilator Therapy in Fontan physiology

  Egbe, A.

  National Heart, Lung, and Blood Institute

  12/20/21 → 11/30/23

  Project: Research project

  • Vasodilator Agents 100%
  • Hemodynamics 60%
  • Lung 59%
  • Vascular Diseases 46%
  • Lung Diseases 42%

• Immunology of xenogeneic extracellular matrix scaffolds for heart valve tissue engineering

  Griffiths, L.

  National Heart, Lung, and Blood Institute

  4/1/21 → 3/31/24

  Project: Research project

  • Heart Valves 100%
  • Pericardium 90%
  • Extracellular Matrix 88%
  • Allergy and Immunology 77%
  • Tissue Engineering 71%

• Optimizing stroke prevention for older adults with atrial fibrillation: Towards rigorous evaluation and judicious application of a new device

  Noseworthy, P. & Yao, X.

  National Institute on Aging

  1/1/20 → 11/30/23

  Project: Research project

  • Atrial Fibrillation 100%
  • Stroke 97%
  • Decision Support Techniques 79%
  • Equipment and Supplies 76%
  • Clinical Trials 63%

• Ventricular and Pulmonary Vascular Reserve after the Fontan Operation

  Egbe, A.

  National Heart, Lung, and Blood Institute

  4/1/18 → 3/31/19

  Project: Research project

  • Ventricular Dysfunction 100%
  • Fontan Procedure 89%
  • Vascular Diseases 72%
  • Lung Diseases 67%
  • Exercise 58%

• ENHANCING CARDIOPOIETIC REGENERATION FOR ISCHEMIC CARDIOMYOPATHY

  Terzic, A.

  National Heart, Lung, and Blood Institute

  12/1/17 → 11/30/18

  Project: Research project

  • Stem Cells 100%
  • Cardiomyopathies 94%
  • Regeneration 73%
  • Cell- and Tissue-Based Therapy 55%
  • Heart Failure 42%

• Pairing Observational and Patient-level Clinical Trial Data to Assess Cardiovascular Risk Reduction with Catheter Ablation for Atrial Fibrillation

  Yao, X. & Noseworthy, P.

  National Heart, Lung, and Blood Institute

  9/15/17 → 8/31/20

  Project: Research project

  • Catheter Ablation 100%
  • Atrial Fibrillation 95%
  • Risk Reduction Behavior 89%
  • Data Warehousing 82%
  • Randomized Controlled Trials 56%

• Small Molecule Discovery for Particulate Guanylyl Cyclase Receptor B Enhancers

  Sangaralingham, S. J., Burnett, J. C. J. & Malany, S.

  National Institute on Aging

  7/15/17 → 5/31/21

  Project: Research project

  • atrial natriuretic factor receptor B 100%
  • Guanylate Cyclase 80%
  • Fibrosis 48%
  • Heart Failure 47%
  • Small Molecule Libraries 30%

• Patient-Oriented Research in Genomic Discovery and Implementation

  Kullo, I. J.

  National Heart, Lung, and Blood Institute

  7/15/17 → 6/30/22

  Project: Research project

  • mentoring 100%
  • medicine 53%
  • conduct of research 48%
  • research project 27%
  • cardiovascular disease 23%

• Diagnostic and Therapeutic Approach to Heart Failure with Preserved Ejection Fraction Based on Circulating Neprilysin

  Pereira, N. L.

  National Institute on Aging

  5/1/17 → 4/30/20

  Project: Research project

  • Neprilysin 100%
  • Heart Failure 45%
  • Diastolic Heart Failure 25%
  • Biomarkers 17%
  • Natriuretic Peptides 10%

• The Role of Autoimmune Mechanisms in the Pathogenesis of Atrial Fibrillation

  Melduni, R.

  National Heart, Lung, and Blood Institute

  1/1/17 → 12/31/17

  Project: Research project

  • Atrial Fibrillation 100%
  • Autoimmune Diseases 18%
  • Cytokines 9%
  • National Heart, Lung, and Blood Institute (U.S.) 7%
  • T-Lymphocytes 6%

• Understanding Caregiving in Heart Failure and Impact on Outcomes

  Dunlay, S. M.

  National Heart, Lung, and Blood Institute

  9/20/16 → 8/31/19

  Project: Research project

  • Heart Failure 100%
  • Social Support 25%
  • Social Networking 19%
  • Spouses 17%
  • Health 17%

• Cardiorenal Fibrosis: Biology and Therapeutics

  Sangaralingham, S. J.

  7/1/16 → 4/30/21

  Project: Research project

  • C-Type Natriuretic Peptide 100%
  • Fibrosis 83%
  • Kidney 54%
  • Guanylate Cyclase 42%
  • atrial natriuretic factor receptor B 37%

• Clinical Implementation of Clopidogrel Pharmacogenetics: The TAILOR-PCI Trial - CCC - Lead Application

  Pereira, N. L., Farkouh, M. E. & Olgin, J. E.

  National Heart, Lung, and Blood Institute

  5/16/16 → 3/31/21

  Project: Research project

  • Cytochrome P-450 CYP2C19 100%
  • Clopidogrel 87%
  • Percutaneous Coronary Intervention 75%
  • Pharmacogenetics 61%
  • Alleles 39%

• Imaging mitochondrial function of progenitor cells transplanted to the ischemic myocardium

  Rodriguez-Porcel, M. G.

  National Heart, Lung, and Blood Institute

  4/11/16 → 3/31/21

  Project: Research project

  • stem cells 100%
  • myocardium 92%
  • image analysis 65%
  • therapeutics 18%
  • reporter genes 16%

• HL-Inorganic Nitrite to Enhance Benefits from Exercise Training in Heart Failure with preserved Ejection Fraction

  Borlaug, B. A.

  National Heart, Lung, and Blood Institute

  4/1/16 → 3/31/21

  Project: Research project

  • Nitrites 100%
  • Exercise 87%
  • Heart Failure 78%
  • Quality of Life 17%
  • Cyclic GMP 12%

• Bimodal platform for nondestructive analysis of engineered vascular biomaterials

  Marcu, L. & Griffiths, L.

  National Heart, Lung, and Blood Institute

  9/1/15 → 5/31/20

  Project: Research project

  • Biomaterials 100%
  • Tissue 78%
  • Scaffolds 77%
  • Ultrasonics 44%
  • Tissue engineering 32%

• Small Molecule Discovery for GC-A Activators

  Burnett, J. C. J.

  7/1/15 → 6/30/18

  Project: Research project

  • peptide B 100%
  • Metabolic Diseases 99%
  • High-Throughput Screening Assays 89%
  • Natriuretic Peptides 78%
  • Atrial Natriuretic Factor 70%

• Peripheral Mechanisms of Cardiopulmonary Control during Exercise

  Olson, T. P.

  National Heart, Lung, and Blood Institute

  5/1/15 → 3/31/21

  Project: Research project

  • Heart Failure 100%
  • Exercise 83%
  • Muscles 29%
  • Hemodynamics 27%
  • Ventilation 22%

• Novel Informatics Approaches for Ascertainment of PAD Status and Adverse Outcomes

  Arruda-Olson, A. M.

  National Heart, Lung, and Blood Institute

  3/15/15 → 2/28/20

  Project: Research project

  • Informatics 100%
  • Epidemiology 26%
  • Electronic medical equipment 24%
  • Genomics 19%
  • Display devices 14%

• Exercise in Genetic Cardiovascular Conditions

  Lampert, R., Ackerman, M. J. & Day, S. M.

  National Heart, Lung, and Blood Institute

  2/1/15 → 1/31/21

  Project: Research project

  • Exercise 100%
  • Long QT Syndrome 58%
  • Quality of Life 38%
  • Sports 26%
  • Patient Advocacy 19%

• Ultrasound Shockwave Therapy for Post-Stenotic Microvascular Remodeling

  Lerman, L. O. & Lerman, A.

  National Heart, Lung, and Blood Institute

  11/15/14 → 10/31/19

  Project: Research project

  • Extracorporeal Shockwave Therapy 100%
  • Metabolic Syndrome 50%
  • Endothelial Progenitor Cells 48%
  • Kidney 33%
  • Swine 12%

• Ventricular remodeling and heart failure after myocardial infarction: a community

  Roger, V. L. & Sarano, M. E.

  National Heart, Lung, and Blood Institute

  1/15/14 → 12/31/18

  Project: Research project

  • Ventricular Remodeling 100%
  • Myocardial Infarction 69%
  • Heart Failure 64%
  • Mitral Valve Insufficiency 17%
  • Biomarkers 15%

• Non-invasive imaging of progenitor cell fate in the ischemic myocardium

  Rodriguez-Porcel, M. G.

  National Heart, Lung, and Blood Institute

  9/20/13 → 12/31/15

  Project: Research project

  • Oxidants 100%
  • Myocardium 71%
  • Reporter Genes 57%
  • Stem Cells 49%
  • Antioxidants 28%

• End of Life Preferences and Healthcare Resource Use in Heart Failure Patients

  Dunlay, S. M.

  National Heart, Lung, and Blood Institute

  8/20/13 → 11/30/18

  Project: Research project

  • Heart Failure 100%
  • Health Services Research 76%
  • Delivery of Health Care 74%
  • Advance Care Planning 53%
  • Mentors 35%

• Xenogeneic Scaffolds for Heart Valve Tissue Engineering

  Griffiths, L. & Griffiths, L. G.

  National Heart, Lung, and Blood Institute

  8/1/13 → 6/30/18

  Project: Research project

  • heart valves 100%
  • pericardium 98%
  • tissue engineering 73%
  • biocompatible materials 44%
  • cattle 43%

• Therapeutic Strategy to slow progression of calcific aortic valve stenosis

  Sarano, M. E., Enriquez-sarano, M. & Schaff, H. V.

  National Center for Advancing Translational Sciences

  6/18/13 → 5/31/14

  Project: Research project

  • Calcification of Aortic Valve 100%
  • Aortic Valve Stenosis 75%
  • Aortic Valve 21%
  • Organized Financing 19%
  • Therapeutics 8%

• Plasma Osteoprotegerin and Adverse Outcomes in CHD Patients

  Kullo, I. J.

  National Heart, Lung, and Blood Institute

  5/15/12 → 4/30/13

  Project: Research project

  • Osteoprotegerin 100%
  • Coronary Disease 61%
  • Fatal Outcome 21%
  • Immunoassay 18%
  • Heart Failure 13%

• Biochemical and Neurohumoral Core

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  8/18/11 → 5/31/16

  Project: Research project

  • Budgets 100%
  • Medicine 64%
  • Research Personnel 61%
  • project 45%
  • assay 37%

• Maximizing the cGMP System in Preclinical Left Ventricular and Renal Dysfunction

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  8/18/11 → 5/31/16

  Project: Research project

  • Left Ventricular Dysfunction 100%
  • Heart Failure 95%
  • Kidney 60%
  • Tadalafil 27%
  • Brain Natriuretic Peptide 20%

• Administrative Core

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  8/18/11 → 5/31/16

  Project: Research project

  • Managers 100%

• Novel Natriuretic Peptides and Delivery for Cardiorenal Disease

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  8/18/11 → 5/31/16

  Project: Research project

  • Designer 100%
  • Natriuretic Peptides 46%

• EHR-based Genomic Discovery and Implementation (Supplement)

  Kullo, I. J., Chute, C. G., Sharp, R. R. & Thibodeau, S. N.

  National Human Genome Research Institute

  8/15/11 → 4/30/24

  Project: Research project

  • Electronic Health Records 100%
  • Medicine 36%
  • Bioethics 19%
  • Datasets 17%
  • Clinical Decision Support Systems 17%

• The Role of The Transient Outward Current In Genetically Elusive Sudden Death

  Giudicessi, J.

  3/1/11 → 5/16/14

  Project: Research project

  • Brugada Syndrome 100%
  • Long QT Syndrome 70%
  • Sudden Death 47%
  • Sudden Cardiac Death 39%
  • Channelopathies 25%

• Role of Endothelial Progenitor Cells in vascular Aging and Calcification

  Lerman, A. & Khosla, S.

  4/15/10 → 3/31/15

  Project: Research project

  • Endothelial Progenitor Cells 100%
  • Vascular Calcification 74%
  • Vascular Diseases 31%
  • Bone and Bones 19%
  • Osteocalcin 17%

• Protein Therapeutics to Prevent Heart Failure Post Myocardial Infarction

  Burnett, J. C. J. & Chen, H. H.

  National Heart, Lung, and Blood Institute

  4/1/10 → 3/31/13

  Project: Research project

  • Myocardial Infarction 100%
  • Heart Failure 89%
  • Brain Natriuretic Peptide 71%
  • Safety 37%
  • Proteins 30%

• Adipokines and Cardiovascular Disease in Diabetes

  Somers, V.

  National Heart, Lung, and Blood Institute

  9/1/09 → 8/31/10

  Project: Research project

  • Adipokines 100%
  • Cardiovascular Diseases 51%
  • Coronary Artery Disease 24%
  • Angioplasty 19%
  • Therapeutics 14%

• Determinants of arterial function in hypertension

  Kullo, I. J.

  National Heart, Lung, and Blood Institute

  7/15/09 → 6/30/10

  Project: Research project

  • Vascular Diseases 100%
  • Proteomics 94%
  • Hypertension 66%
  • Molecular Epidemiology 60%
  • Vascular Stiffness 60%

• Role of Oxidative Stress in Stem Cell Differentiation and Survival

  Rodriguez-Porcel, M. G.

  National Heart, Lung, and Blood Institute

  6/3/09 → 5/31/12

  Project: Research project

  • Stem Cells 100%
  • Cell Differentiation 95%
  • Oxidative Stress 79%
  • Solar System 47%
  • Myocardial Infarction 42%

• Lp-PLA2 and Coronary Atherosclerosis in Humans

  Lerman, A.

  4/1/09 → 3/31/15

  Project: Research project

  • 1-Alkyl-2-acetylglycerophosphocholine Esterase 100%
  • Coronary Artery Disease 27%
  • Inflammation 16%
  • Blood Vessels 16%
  • Oxidative Stress 16%

• Catheter Ablation versus Antiarrythmic Drug Therapy for Atrial Fibrilllation Tria

  Packer, D. L.

  National Heart, Lung, and Blood Institute

  2/1/09 → 6/30/17

  Project: Research project

  • Atrial Fibrillation 100%
  • Catheter Ablation 99%
  • Drug Therapy 45%
  • Mortality 36%
  • Anti-Arrhythmia Agents 35%

• Molecular Mechanisms Mediating Resistance to Leptin Signaling During Fat Gain

  Somers, V. & Somers, V. K.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/30/08 → 8/31/09

  Project: Research project

  • Leptin 100%
  • Caveolin 1 46%
  • Fats 45%
  • Weight Gain 42%
  • Weight Loss 25%

• Estrogen, Platelets, and Artherosclerosis

  Bailey, K. R., Heit, J. A., Miller, V. M., Owen, W. G. & Miller, V. M.

  National Heart, Lung, and Blood Institute

  1/10/08 → 12/31/13

  Project: Research project

  • menopause 100%
  • cardiovascular disease 49%
  • animal 31%
  • heredity 23%
  • experiment 23%

• Role of Oxidative Stress in Stem Cell Differentiation and Survival

  Rodriguez-Porcel, M. G.

  National Heart, Lung, and Blood Institute

  12/1/06 → 5/31/09

  Project: Research project

  • Stem Cells 100%
  • Cell Differentiation 98%
  • Oxidative Stress 77%
  • Myocardial Infarction 34%
  • Optical Imaging 26%

• Altitude Symptoms at the South Pole

  Johnson, B. D., Beck, K. C., Turner, S. T., Bailey, K. R. & Hickman, J. J. R.

  National Science Foundation

  10/1/06 → 4/30/11

  Project: Research project

  • Oxygen 100%
  • Mountaineering 80%
  • Genes 75%
  • Air Travel 72%
  • School Teachers 65%

• Mayo Heart Failure Regional Clinical Center

  Redfield, M. M. & Redfield, M. M.

  National Heart, Lung, and Blood Institute

  9/30/06 → 12/31/11

  Project: Research project

  • Heart Failure 100%
  • Brain Natriuretic Peptide 72%
  • Cardio-Renal Syndrome 50%
  • Diastolic Heart Failure 32%
  • Type 5 Cyclic Nucleotide Phosphodiesterases 32%

• Cardiovascular Peptides and Myocardial Infarction

  Burnett, J. C. J., Burnett, J. C. J. & Chen, H. H.

  National Heart, Lung, and Blood Institute

  8/1/06 → 7/31/09

  Project: Research project

  • Natriuretic Peptides 100%
  • Myocardial Infarction 77%
  • Peptides 48%
  • Guanylate Cyclase 40%
  • atrial natriuretic factor receptor A 38%

• Endothelial BK Channel Regulation by Caveolae Targeting

  Lee, H. C. & Lee, H. C.

  7/1/06 → 6/30/12

  Project: Research project

  • Large-Conductance Calcium-Activated Potassium Channels 100%
  • Caveolae 56%
  • Caveolin 1 46%
  • Endothelial Cells 20%
  • caveolin-1 (82-101) 15%

• Cardioprotective Repair through Cardiopoiesis

  Terzic, A. & Terzic, A.

  1/1/06 → 12/31/12

  Project: Research project

  • Stem Cells 100%
  • Embryoid Bodies 68%
  • Endoderm 42%
  • Myocardial Infarction 37%
  • Embryonic Stem Cells 36%

• Biology and Novel Therapeutics of Cardiovascular Peptides

  Burnett, J. C. J., Chen, H. H., Redfield, M. M., Simari, R. D. & Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  8/15/05 → 6/30/16

  Project: Research project

  • Natriuretic Peptides 100%
  • atrial natriuretic factor receptor A 48%
  • Cyclic GMP 46%
  • Peptides 36%
  • Guanylate Cyclase-Coupled Receptors 34%