Viral encephalitis: Etiology, clinical features, diagnosis and management

Sergio Ferrari, Antonio Toniolo, Salvatore Monaco, Filippo Luciani, Francesca Cainelli, Andreina Baj, Zelalem Temesgen, Sandro Vento

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Viral encephalitis is worldwide spread pathology with high morbidity and mortality. Its incidence is higher in children. Enteroviruses, varicella zoster virus and herpes simplex viruses are the most frequent agents. However, in spite of the use of modern microbiological and radiological methods, an etiological diagnosis is reached in less than 50% of cases, making a careful differential diagnosis with non viral brain diseases imperative. Pathogenesis is elusive and therapy continues to remain supportive in almost all cases, as the only virus-directed treatment is available for herpesvirus-related encephalitis and a role for steroids continues to be debated. Novel and more targeted therapies are eagerly needed.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalOpen Infectious Diseases Journal
Issue number1
StatePublished - 2009

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Infectious Diseases


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